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Many people with inflammatory bowel disease (IBD) also have mental health issues. Eva Szigethy, a psychiatrist at the University of Pittsburgh in Pennsylvania, studies how cognitive therapy can help people with gastrointestinal problems. She spoke to Nature about the relationship between mental health and IBD.
Helminths are worms that can live in the human intestine. Joel Weinstock, a gastroenterologist at Tufts Medical Center in Boston, Massachusetts, studies how they affect inflammation and the body's immune response. He spoke to Nature about how helminths might lead to treatments for inflammatory bowel disease (IBD).
Identification of a previously uncharacterized genetic disease highlights DNA repair as a shared mechanism in neurodegenerative disorders, and suggests potential therapeutic approaches to tackling them. See Letter p.87
The Piezo2 protein senses changes in lung volume, acting in different neurons to convey this information to the brain. This finding adds to the list of roles for Piezo2 in mechanosensation. See Article p.176
A molecular modification called m6Am has been found to regulate the stability of messenger RNAs in mammalian cells. The mechanism casts fresh light on how reversibly modified RNA bases control the fate of mRNA. See Article p.371