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  • In situ self-assembly is advantageous for cancer therapy and imaging because of the efficient deep-tumour targeting, enhanced blood circulation and negligible drug resistance of the resulting nanomedicines. This Review discusses extracellular and intracellular in situ self-assembly based on endogenous and exogenous stimuli for cancer therapy and imaging applications.

    • Jaewon Kim
    • Sungkyu Lee
    • Jong Seung Kim
    Review Article
  • Two-dimensional materials can enable a new generation of flexible and printed electronics suitable for light-weight, low-power, sustainable and cost-effective field-effect transistors. This Review surveys solution-processed transistors based on 2D materials, discussing their performance, limitations and future perspectives.

    • Silvia Conti
    • Gabriele Calabrese
    • Gianluca Fiori
    Review Article
  • Combining poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) with 3D-printing techniques enables the customization of compliant conductive materials for soft robotics, towards the goal of merging humans and robots. This Review discusses the fundamentals of 3D-printed PEDOT:PSS for soft robotics, from printable ink design and evaluation to printing strategies and promising soft robotic systems.

    • Jinhao Li
    • Jie Cao
    • Guoying Gu
    Review Article
  • An article in Nano Letters presents a method to transfer metallic nanopatterns to soft matter such as tissues or single cells.

    • Charlotte Allard
    Research Highlight
  • UV photodetectors based on low-dimensional wide-bandgap semiconductors offer wearable, multidimensional and intelligent functions in the scenarios of imaging, communication, multispectral and/or weak light detection and flexible electronics. This Review focuses on the material design, dimensionality engineering and device engineering of wide-bandgap semiconductors in diversified UV applications.

    • Ziqing Li
    • Tingting Yan
    • Xiaosheng Fang
    Review Article
  • Sorption working pairs, which can convert low-grade heat into cold energy or seasonally store thermal energy, are potential future carbon-neutral materials for thermal management. This Comment highlights the superiorities of metal–organic framework (MOF)–ammonia working pairs for adaptable thermal management under extreme climates and discusses strategies to design MOFs with high stability and ammonia sorption capacity.

    • Shao-Fei Wu
    • Bing-Zhi Yuan
    • Li-Wei Wang
    Comment
  • Deaf scientists who use American Sign Language need to be able to communicate specialized concepts with ease. In this Viewpoint, four deaf scientists — a quantum physicist, a marine ecologist, an immunologist and an organic chemist — discuss their experiences in developing scientific lexicons and the resulting shift in their science communication.

    • Colin P. Lualdi
    • Barbara Spiecker
    • Kaitlyn Clark
    Viewpoint
  • Nature provides an endless source of inspiration for advanced materials, fuelled by evolutionary innovations over many millions of years. Capitalizing on this wealth of biological solutions requires an approach to materials innovation that is informed by a holistic understanding of multi-functional biological systems and leverages the defining feature of the natural world — diversity.

    • Devi Stuart-Fox
    • Leslie Ng
    • Gregory S. Watson
    Comment
  • Although perovskite solar cells now have competitive efficiencies compared with silicon solar cells, their low stability has hindered their commercial application thus far. This Review summarizes the tremendous improvements made over the past decade and offer a perspective on how to reach >25-year stable perovskite solar cells.

    • Hongwei Zhu
    • Sam Teale
    • Osman M. Bakr
    Review Article
  • Active learning and automation will not easily liberate humans from laboratory workflows. Before they can really impact materials research, artificial intelligence systems will need to be carefully set up to ensure their robust operation and their ability to deal with both epistemic and stochastic errors. As autonomous experiments become more widely available, it is essential to think about how to embed reproducibility, reconfigurability and interoperability in the design of autonomous labs.

    • Zhichu Ren
    • Zekun Ren
    • Ju Li
    Comment
  • Nanotheranostics — nanoparticle-based systems combining diagnostic and therapeutic functions — hold great promise, but their implementation in the clinic is challenging. This Review discusses the design and clinical development of nanotheranostics and defines the critical steps needed to overcome technical, manufacturing, regulatory and economical challenges for their safe and effective clinical translation.

    • Peter J. Gawne
    • Miguel Ferreira
    • Paolo Decuzzi
    Review Article
  • An article in the Journal of the American Chemical Society reports a 3D covalent organic framework made from simple 2D building blocks.

    • Jet-Sing M. Lee
    Research Highlight
  • Sodium-ion batteries (SIBs), an emerging type of sustainable battery, still need to be recycled for environmental and economic reasons. Strategies to recycle spent SIBs should be made during the initial stages of commercialization to ensure that SIBs are designed for ease of recycling, efficiency and low operation costs. This Perspective article summarizes the material components of SIBs, discusses strategies for their recycling and outlines the associated challenges and future outlook of SIB recycling.

    • Yun Zhao
    • Yuqiong Kang
    • Baohua Li
    Perspective
  • An article in Nature Nanotechnology reports a nanopore-based single-molecule sensing method that allows control over the translocation speed of the measured molecule.

    • Charlotte Allard
    Research Highlight
  • An article in Advanced Materials reports an entropy tuning strategy to design sodium-ion battery electrolytes that adapt to low temperatures, enabling rechargeable batteries that work in the extreme cold.

    • Ariane Vartanian
    Research Highlight
  • An article in Nature Nanotechnology reports ferroelectric field-effect transistors that are compatible with Si complementary metal–oxide–semiconductor back-end-of-line processes.

    • Lishu Wu
    Research Highlight
  • An article in Advanced Materials reports molecules designed following the A-D-A′-D-A structure that exhibit efficient emission beyond 1,100 nm.

    • Charlotte Allard
    Research Highlight