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In 653,790 individuals, this multi-ancestral meta-analysis of tobacco use disorder finds 461 potential risk genes and hundreds of associations with health outcomes, showcasing the utility of electronic health records for genetic research.
The combination of general anaesthesia and neuroimaging holds unique potential for catalysing integrative and translational discovery about human brains and consciousness. By spanning molecular, cognitive and clinical neuroscience, anaesthesia provides a bridge from molecules to mind across species.
This pre-registered systematic review and multilevel meta-analysis examined the effects of receiving touch for promoting mental and physical well-being, quantifying the efficacy of touch interventions for different ways of administration.
In this large-scale exome-wide association study, Deng, Wu, Yang, He et al. report genetic associations of protein-coding variants with neurodegenerative diseases and mental disorders, including for 50 new genes.
Researchers have a wide variety of choices when it comes to careers. Often, post-PhD, we leave academic research for industry. But it is also possible to transition back, when done carefully. In this how-to, I outline how to transition between industry and academic research and vice versa.
Our study successfully tracks salient distracting signals in high-frequency activity obtained from human intracranial recordings. We observed that the temporal lobe has a critical role in reacting to salient distractors, whereas the parietal and frontal cortices seem to be less important than previously thought.
This study uses a unique dataset with intracranial electroencephalography recordings from 18 neurosurgical patients performing a visual search task to uncover neuronal network dynamics and brain regions associated with attentional capture.
We all care about effect sizes. Yet, traditional ways of evaluating them (P< 0.05 and generic benchmarks) are failing us. We propose two paths forward: setting better, contextualized benchmarks or — more radically — letting go of benchmarks altogether. Both paths point to adjusted expectations, more detailed reporting and slow science.
Large language models can generate sophisticated text or code with little input from a user, which has the potential to impoverish our own writing and thinking skills. We need to understand the effect of this technology on our cognition and to decide whether this is what we want.
Given the increasing sophistication of virtual reality systems in providing immersive nature experiences, there is the potential for analogous health benefits to those that arise from real nature experiences. We call for research to better understand the human–nature–technology interaction to overcome potential pitfalls of the technology and design tailored virtual experiences that can deliver health outcomes and wellbeing across society.
Among 406,438 adults in the UK, Wang et al. find that people with SARS-CoV-2 infection were at increased risk (at 1 year) of incident and prevalent psychiatric disorders and psychotropic prescriptions, especially those hospitalized for COVID-19 or those not fully vaccinated.
This study demonstrates the decomposition of an odour compound in olfactory perception and central neural representation and establishes a direct correspondence between the coding of submolecular chemical features and odour quality.
Which interventions limit the spread of COVID-19 misinformation online? In an experiment on Facebook Messenger in Kenya and Nigeria, nudges to consider an information’s accuracy worked best.
Challenging long-held assumptions, this research reveals that people can learn to control bionic hands just as effectively, and in some ways better, using arbitrary control strategies compared with control strategies that mimic the human body.
Developmental language disorder is a common neurodevelopmental disorder whose adverse impacts continue into adulthood, but its neural bases have been unclear. This systematic review and meta-analysis identified and synthesized neuroanatomical studies of developmental language disorder using co-localization likelihood estimation.
The authors field test the transferability of behavioural science knowledge on promoting COVID-19 booster uptake. Interventions effective in past field work improve uptake, but those deemed effective in surveys measuring intentions or predictions do not.