ADVANCE ONLINE PUBLICATION

The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
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July 25 2008

Original Articles

Collagen alpha1(XI) in normal and malignant breast tissue

Karen C Halsted, Kara B Bowen, Laura Bond, Sarah E Luman, Cheryl L Jorcyk, William E Fyffe, Joseph D Kronz and Julia T Oxford

Mod Pathol advance online publication, July 25, 2008; doi:10.1038/modpathol.2008.129

Atypical lobular hyperplasia and classic lobular carcinoma in situ in core biopsy specimens: routine excision is not necessary

Helena Hwang, Lora D Barke, Ellen B Mendelson and Barbara Susnik

Mod Pathol advance online publication, July 25, 2008; doi:10.1038/modpathol.2008.134

Inducible nitric oxide synthase expression in melanoma: implications in lymphangiogenesis

Daniela Massi, Maria C De Nisi, Alessandro Franchi, Vasileios Mourmouras, Gianna Baroni, John Panelos, Marco Santucci and Clelia Miracco

Mod Pathol advance online publication, July 25, 2008; doi:10.1038/modpathol.2008.128

Sporadic clear cell renal cell carcinoma but not the papillary type is characterized by severely reduced frequency of primary cilia

Peter Schraml, Ian J Frew, Claudio R Thoma, Gunther Boysen, Kirsten Struckmann, Wilhelm Krek and Holger Moch

Mod Pathol advance online publication, July 25, 2008; doi:10.1038/modpathol.2008.132

Epidermal growth factor receptor protein expression and gene amplification in the chemorefractory metastatic embryonal carcinoma

Xiaoyan Wang, Shaobo Zhang, Gregory T MacLennan, Katharina Biermann, Richard S Foster, Stephen D Beck and Liang Cheng

Mod Pathol advance online publication, July 25, 2008; doi:10.1038/modpathol.2008.133

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July 11 2008

Original Articles

Clinicopathological features and global genomic copy number alterations of pilomyxoid astrocytoma in the hypothalamus/optic pathway: comparative analysis with pilocytic astrocytoma using array-based comparative genomic hybridization

Yoon-Kyung Jeon, Jung-Eun Cheon, Seung-Ki Kim, Kyu-Chang Wang, Byung-Kyu Cho and Sung-Hye Park

Mod Pathol advance online publication, July 11, 2008; doi:10.1038/modpathol.2008.88

Cartilaginous features in matrix-producing carcinoma of the breast: four cases report with histochemical and immunohistochemical analysis of matrix molecules

Kimihide Kusafuka, Koji Muramatsu, Masako Kasami, Ken Kuriki, Kumiko Hirobe, Isamu Hayashi, Hideto Watanabe, Yuji Hiraki, Chisa Shukunami, Toru Mochizuki and Toru Kameya

Mod Pathol advance online publication, July 11, 2008; doi:10.1038/modpathol.2008.120

N-cadherin serves as diagnostic biomarker in intrahepatic and perihilar cholangiocarcinomas

Jean-François Mosnier, Christine Kandel, Dominique Cazals-Hatem, Chantal Bou-Hanna, Jérome Gournay, Anne Jarry and Christian L Laboisse

Mod Pathol advance online publication, July 11, 2008; doi:10.1038/modpathol.2008.123

Global DNA hypomethylation in intratubular germ cell neoplasia and seminoma, but not in nonseminomatous male germ cell tumors

Georges J Netto, Yasutomo Nakai, Masashi Nakayama, Sana Jadallah, Antoun Toubaji, Norio Nonomura, Roula Albadine, Jessica L Hicks, Jonathan I Epstein, Srinivasan Yegnasubramanian, William G Nelson and Angelo M De Marzo

Mod Pathol advance online publication, July 11, 2008; doi:10.1038/modpathol.2008.127

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July 4 2008

Original Articles

Heterogeneous genetic profiles in soft tissue myoepitheliomas

Karolin H Hallor, Manuel R Teixeira, Christopher D M Fletcher, Susana Bizarro, Johan Staaf, Henryk A Domanski, Fredrik Vult von Steyern, Ioannis Panagopoulos, Nils Mandahl and Fredrik Mertens

Mod Pathol advance online publication, July 4, 2008; doi:10.1038/modpathol.2008.124

Immunohistochemistry for human concentrative nucleoside transporter 3 protein predicts fludarabine sensitivity in chronic lymphocytic leukemia

Roger Y Tsang, Cheryl Santos, Sunita Ghosh, Laith Dabbagh, Karen King, James Young, Carol E Cass, John R Mackey and Raymond Lai

Mod Pathol advance online publication, July 4, 2008; doi:10.1038/modpathol.2008.110

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June 27 2008

Original Articles

Thyroidectomies from patients with history of therapeutic radiation during childhood and adolescence have a unique mutational profile

Adel Assaad, Laura Voeghtly and Jennifer L Hunt

Mod Pathol advance online publication, June 27, 2008; doi:10.1038/modpathol.2008.122

MicroRNA analysis as a potential diagnostic tool for papillary thyroid carcinoma

Yao-Tseng Chen, Naoki Kitabayashi, Xi K Zhou, Thomas J Fahey III and Theresa Scognamiglio

Mod Pathol advance online publication, June 27, 2008; doi:10.1038/modpathol.2008.105

Interobserver variability and aberrant E-cadherin immunostaining of lobular neoplasia and infiltrating lobular carcinoma

Young J Choi, Marguerite M Pinto, Liming Hao and Ali K Riba

Mod Pathol advance online publication, June 27, 2008; doi:10.1038/modpathol.2008.106

Malignant mesothelioma with heterologous elements: clinicopathological correlation of 27 cases and literature review

Sonja Klebe, Annabelle Mahar, Douglas W Henderson and Victor L Roggli

Mod Pathol advance online publication, June 27, 2008; doi:10.1038/modpathol.2008.125

The diagnostic and prognostic utility of claudin expression in renal cell neoplasms

Mirna Lechpammer, Murray B Resnick, Edmond Sabo, Evgeny Yakirevich, Wesley O Greaves, Katherine T Sciandra, Rosemarie Tavares, Lelia C Noble, Ronald A DeLellis and Li J Wang

Mod Pathol advance online publication, June 27, 2008; doi:10.1038/modpathol.2008.116

Differential diagnostic and functional role of the multi-marker phenotype CDX2/CK20/CK7 in colorectal cancer stratified by mismatch repair status

Alessandro Lugli, Alexandar Tzankov, Inti Zlobec and Luigi Maria Terracciano

Mod Pathol advance online publication, June 27, 2008; doi:10.1038/modpathol.2008.117

Salivary gland-type lung carcinomas: an EGFR immunohistochemical, molecular genetic, and mutational analysis study

Ricardo S Macarenco, Timothy S Uphoff, Heather Flynn Gilmer, Robert B Jenkins, Stephen N Thibodeau, Jean E Lewis, Julian R Molina, Ping Yang and Marie-Christine Aubry

Mod Pathol advance online publication, June 27, 2008; doi:10.1038/modpathol.2008.113

A subset of cranial fasciitis is associated with dysregulation of the Wnt/beta-catenin pathway

Dinesh Rakheja, Jacqulin C Cunningham, Midori Mitui, Ashish S Patel, Gail E Tomlinson and Arthur G Weinberg

Mod Pathol advance online publication, June 27, 2008; doi:10.1038/modpathol.2008.112

MASH1: a useful marker in differentiating pulmonary small cell carcinoma from Merkel cell carcinoma

Jonathan Ralston, Luis Chiriboga and Daisuke Nonaka

Mod Pathol advance online publication, June 27, 2008; doi:10.1038/modpathol.2008.118

The expression of NeuroD and mASH1 in the gastroenteropancreatic neuroendocrine tumors

Takashi Shida, Mitsuko Furuya, Takashi Kishimoto, Takashi Nikaido, Tohru Tanizawa, Keiji Koda, Kenji Oda, Shigetsugu Takano, Fumio Kimura, Hiroaki Shimizu, Hiroyuki Yoshidome, Masayuki Ohtsuka, Yukio Nakatani and Masaru Miyazaki

Mod Pathol advance online publication, June 27, 2008; doi:10.1038/modpathol.2008.121

Disrupted cell adhesion but not proliferation mediates cyst formation in polycystic liver disease

Esmé Waanders, J Han J M Van Krieken, Anke L L Lameris and Joost P H Drenth

Mod Pathol advance online publication, June 27, 2008; doi:10.1038/modpathol.2008.115

Fluorescence in situ hybridization is a useful ancillary diagnostic tool for extraskeletal myxoid chondrosarcoma

Wei-Lien Wang, Empar Mayordomo, Bogdan A Czerniak, Lynne V Abruzzo, Paola Dal Cin, Dejka M Araujo, Dina C Lev, Dolores López-Terrada and Alexander JF Lazar

Mod Pathol advance online publication, June 27, 2008; doi:10.1038/modpathol.2008.114

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June 20 2008

Original Articles

Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis

Bora Gurel, Tsuyoshi Iwata, Cheryl M Koh, Robert B Jenkins, Fusheng Lan, Chi Van Dang, Jessica L Hicks, James Morgan, Toby C Cornish, Siobhan Sutcliffe, William B Isaacs, Jun Luo and Angelo M De Marzo

Mod Pathol advance online publication, June 20, 2008; doi:10.1038/modpathol.2008.111

Immunophenotyping of serous carcinoma of the female genital tract

Sharon Nofech-Mozes, Mahmoud A Khalifa, Nadia Ismiil, Reda S Saad, Wedad M Hanna, Al Covens and Zeina Ghorab

Mod Pathol advance online publication, June 20, 2008; doi:10.1038/modpathol.2008.108

Cellular localization of EMMPRIN predicts prognosis of patients with operable lung adenocarcinoma independent from MMP-2 and MMP-9

Wulf Sienel, Bernhard Polzer, Karimah Elshawi, Michael Lindner, Alicia Morresi-Hauf, Christian Vay, Fabian Eder, Bernward Passlick and Christoph A Klein

Mod Pathol advance online publication, June 20, 2008; doi:10.1038/modpathol.2008.102

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June 13 2008

Original Articles

Biomarker (ProExTM C, p16INK4A, and MiB-1) distinction of high-grade squamous intraepithelial lesion from its mimics

Alvaro P Pinto, Nicolas F Schlecht, Terri Y C Woo, Christopher P Crum and Edmund S Cibas

Mod Pathol advance online publication, June 13, 2008; doi:10.1038/modpathol.2008.101

Nuclear to non-nuclear Pmel17/gp100 expression (HMB45 staining) as a discriminator between benign and malignant melanocytic lesions

Bonnie E Gould Rothberg, Christopher B Moeder, Harriet Kluger, Ruth Halaban, David E Elder, George F Murphy, Alexander Lazar, Victor Prieto, Lynn McDivitt Duncan and David L Rimm

Mod Pathol advance online publication, June 13, 2008; doi:10.1038/modpathol.2008.100

Clinical significance of p53 alterations in surgically treated prostate cancers

Thorsten Schlomm, Liv Iwers, Patrick Kirstein, Birte Jessen, Jens Köllermann, Sarah Minner, Annika Passow-Drolet, Martina Mirlacher, Karin Milde-Langosch, Markus Graefen, Alexander Haese, Thomas Steuber, Ronald Simon, Hartwig Huland, Guido Sauter and Andreas Erbersdobler

Mod Pathol advance online publication, June 13, 2008; doi:10.1038/modpathol.2008.104

Cadherin-17 is a useful diagnostic marker for adenocarcinomas of the digestive system

Min-Cheng Su, Ray-Hwang Yuan, Chiao-Ying Lin and Yung-Ming Jeng

Mod Pathol advance online publication, June 13, 2008; doi:10.1038/modpathol.2008.107

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June 6 2008

Original Articles

Expression of basal keratins and vimentin in breast cancers of young women correlates with adverse pathologic parameters

Maureen Hong-Sing Chen, George Wai-Cheong Yip, Gary Man-Kit Tse, Takuya Moriya, Philip Chi-Wai Lui, Mar-Lwin Zin, Boon-Huat Bay and Puay-Hoon Tan

Mod Pathol advance online publication, June 6, 2008; doi:10.1038/modpathol.2008.90

Clear cell carcinoma of the pancreas: histopathologic features and a unique biomarker: hepatocyte nuclear factor-1beta

Lisa Kim, Jie Liao, Meng Zhang, Mark Talamonti, David Bentrem, Sambasiva Rao and and Guang-Yu Yang

Mod Pathol advance online publication, June 6, 2008; doi:10.1038/modpathol.2008.95

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May 23 2008

Original Articles

Expression of c-kit in fibroepithelial lesions of the breast is a mast cell phenomenon

Bojana Djordjevic and Wedad M Hanna

Mod Pathol advance online publication, May 23, 2008; doi:10.1038/modpathol.2008.78

Adrenal gland hemorrhage in patients with fatal bacterial infections

Jeannette Guarner, Christopher D Paddock, Jeanine Bartlett and Sherif R Zaki

Mod Pathol advance online publication, May 23, 2008; doi:10.1038/modpathol.2008.98

Gastric hyperplastic polyps in post transplant patients: a clinicopathologic study

Kim D Jewell, Daniel L Toweill, Paul E Swanson, Melissa P Upton and Matthew M Yeh

Mod Pathol advance online publication, May 23, 2008; doi:10.1038/modpathol.2008.87

Parameters of perineural invasion in radical prostatectomy specimens lack prognostic significance

A David Merrilees, Peter B Bethwaite, Grant L Russell, Richard G Robinson and Brett Delahunt

Mod Pathol advance online publication, May 23, 2008; doi:10.1038/modpathol.2008.81

Absence of TMPRSS2:ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome

Maisa Yoshimoto, Anthony M Joshua, Isabela W Cunha, Renata A Coudry, Francisco P Fonseca, Olga Ludkovski, Maria Zielenska, Fernando A Soares and Jeremy A Squire

Mod Pathol advance online publication, May 23, 2008; doi:10.1038/modpathol.2008.96

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May 16 2008

Original Article

High concordance between immunohistochemistry and fluorescence in situ hybridization testing for HER2 status in breast cancer requires a normalized IHC scoring system

Allen M Gown, Lynn C Goldstein, Todd S Barry, Steven J Kussick, Patricia L Kandalaft, Patricia M Kim and Christopher C Tse

Mod Pathol advance online publication, May 16, 2008; doi:10.1038/modpathol.2008.83

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May 9 2008

Original Articles

WT1 immunoreactivity in breast carcinoma: selective expression in pure and mixed mucinous subtypes

Akosua B Domfeh, AnnaMarie L Carley, Joan M Striebel, Rouzan G Karabakhtsian, Anca V Florea, Kim McManus, Sushil Beriwal and Rohit Bhargava

Mod Pathol advance online publication, May 9, 2008; doi:10.1038/modpathol.2008.69

Reduced E-cadherin expression correlates with disease progression in Paget's disease of the vulva but not Paget's disease of the breast

Patricia E Ellis, Salvador Diaz Cano, Mark Fear, David P Kelsell, Lucy Ghali, Julie C Crow, Christopher W Perrett and Allan B MacLean

Mod Pathol advance online publication, May 9, 2008; doi:10.1038/modpathol.2008.50

Tumor infiltrating lymphocytes differ in invasive micropapillary carcinoma and medullary carcinoma of breast

Xiaojing Guo, Yu Fan, Ronggang Lang, Feng Gu, Ling Chen, Lifang Cui, Gordon A Pringle, Xinmin Zhang and Li Fu

Mod Pathol advance online publication, May 9, 2008; doi:10.1038/modpathol.2008.72

Diagnostic and Prognostic Utility of Molecular Markers in Synchronous Bilateral Breast Carcinoma

Reda S Saad, Krista L Denning, Sydney D Finkelstein, Yulin Liu, Telma C Pereira, Xiaoqi Lin and Jan F Silverman

Mod Pathol advance online publication, May 9, 2008; doi:10.1038/modpathol.2008.35

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March 21 2008

Original Article

Histopathologic variables predict Oncotype DX Recurrence Score

Melina B Flanagan, David J Dabbs, Adam M Brufsky, Sushil Beriwal and Rohit Bhargava

Mod Pathol advance online publication, March 21, 2008; doi:10.1038/modpathol.2008.54

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March 7 2008

Original Article

Cyclin D1 expression analysis in familial breast cancers may discriminate BRCAX from BRCA2-linked cases

Mara Colombo, Monica Giarola, Luigi Mariani, Carla B Ripamonti, Virna De Benedetti, Michele Sardella, Marco Losa, Siranoush Manoukian, Bernard Peissel, Marco A Pierotti, Silvana Pilotti and Paolo Radice

Mod Pathol advance online publication, March 7, 2008; doi:10.1038/modpathol.2008.43

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January 25 2008

Original Article

Immunohistochemical detection of XIAP and p63 in adenomatous hyperplasia, atypical adenomatous hyperplasia, bronchioloalveolar carcinoma and well-differentiated adenocarcinoma

Maoxin Wu, Lurmag Orta, Joan Gil, Gan Li, Alice Hu and David E Burstein

Mod Pathol advance online publication, January 25, 2008; doi:10.1038/modpathol.3801056

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