TABLE OF CONTENTS
Volume 20, Issue 5 (May 2006)
Review
The role of p73 in hematological malignancies
A Pluta, U Nyman, B Joseph, T Robak, B Zhivotovsky and P Smolewski
Leukemia 20: 757-766; advance online publication, March 16, 2006; doi:10.1038/sj.leu.2404166
Editorial
Modulation of cellular behavior by exogenous messenger RNA
P Ponsaerts and Z N Berneman
Leukemia 20: 767-769; doi:10.1038/sj.leu.2404219
Original Articles
Acute Leukemias
Risk score model for fatal intracranial hemorrhage in acute leukemia
H Kim, J-H Lee, S-J Choi, J-H Lee, M Seol, Y S Lee, W-K Kim, J-S Lee and K-H Lee
Leukemia 20: 770-776; advance online publication, March 9, 2006; doi:10.1038/sj.leu.2404148
The MLL recombinome of acute leukemias
C Meyer, B Schneider, S Jakob, S Strehl, A Attarbaschi, S Schnittger, C Schoch, M W J C Jansen, J J M van Dongen, M L den Boer, R Pieters, M-G Ennas, E Angelucci, U Koehl, J Greil, F Griesinger, U zur Stadt, C Eckert, T Szczepa
ski, F K Niggli, B W Schäfer, H Kempski, H J M Brady, J Zuna, J Trka, L L Nigro, A Biondi, E Delabesse, E Macintyre, M Stanulla, M Schrappe, O A Haas, T Burmeister, T Dingermann, T Klingebiel and R Marschalek
Leukemia 20: 777-784; advance online publication, March 2, 2006; doi:10.1038/sj.leu.2404150
Acute Non-Lymphoblastic Leukemias
A novel retinoic/butyric hyaluronan ester for the treatment of acute promyelocytic leukemia: preliminary preclinical results
D Coradini, C Pellizzaro, I Scarlata, S Zorzet, C Garrovo, G Abolafio, A Speranza, M Fedeli, S Cantoni, G Sava, M G Daidone and A Perbellini
Leukemia 20: 785-792; advance online publication, March 9, 2006; doi:10.1038/sj.leu.2404179
Chronic Myeloproliferative Disorders
Prediction of relapse by day 100 BCR-ABL quantification after allogeneic stem cell transplantation for chronic myeloid leukemia
V Asnafi, M-T Rubio, E Delabesse, E Villar, F Davi, G Damaj, I Hirsch, N Dhédin, J P Vernant, B Varet, A Buzyn and E Macintyre
Leukemia 20: 793-799; advance online publication, March 16, 2006; doi:10.1038/sj.leu.2404170
Chronic Lymphocytic Leukemia
DHMEQ, a new NF-
B inhibitor, induces apoptosis and enhances fludarabine effects on chronic lymphocytic leukemia cells
R Horie, M Watanabe, T Okamura, M Taira, M Shoda, T Motoji, A Utsunomiya, T Watanabe, M Higashihara and K Umezawa
Leukemia 20: 800-806; advance online publication, March 9, 2006; doi:10.1038/sj.leu.2404167
Myeloma
Prognostic factors for hyperdiploid-myeloma: effects of chromosome 13 deletions and IgH translocations
W J Chng, R Santana-Dávila, S A Van Wier, G J Ahmann, S M Jalal, P L Bergsagel, M Chesi, M C Trendle, S Jacobus, E Blood, M M Oken, K Henderson, R A Kyle, M A Gertz, M Q Lacy, A Dispenzieri, P R Greipp and R Fonseca
Leukemia 20: 807-813; advance online publication, March 2, 2006; doi:10.1038/sj.leu.2404172
Therapy
High survival rate with the LMT-89 regimen in lymphoblastic lymphoma (LL), but not in T-cell acute lymphoblastic leukemia (T-ALL)
E Jabbour, S Koscielny, C Sebban, N Peslin, C Patte, T Gargi, P Biron, C Fermé, J H Bourhis, J M Vantelon, P Arnaud and V Ribrag
Leukemia 20: 814-819; advance online publication, March 2, 2006; doi:10.1038/sj.leu.2404156
Sensitivity and Resistance to Therapy
Unsupervised proteome analysis of human leukaemia cells identifies the Valosin-containing protein as a putative marker for glucocorticoid resistance
M Lauten, A Schrauder, C Kardinal, J Harbott, K Welte, B Schlegelberger, M Schrappe and N von Neuhoff
Leukemia 20: 820-826; advance online publication, March 16, 2006; doi:10.1038/sj.leu.2404162
Oncogenes, Fusion Genes and Tumor Suppressor Genes
Identification of a novel imatinib responsive KIF5B-PDGFRA fusion gene following screening for PDGFRA overexpression in patients with hypereosinophilia
J Score, C Curtis, K Waghorn, M Stalder, M Jotterand, F H Grand and N C P Cross
Leukemia 20: 827-832; advance online publication, February 23, 2006; doi:10.1038/sj.leu.2404154
Animal Models
Evaluation of ex vivo expanded human NK cells on antileukemia activity in SCID-beige mice
F Guimarães, H Guven, D Donati, B Christensson, H G Ljunggren, M T Bejarano and M S Dilber
Leukemia 20: 833-839; advance online publication, March 2, 2006; doi:10.1038/sj.leu.2404147
Cytogenetics and Molecular Genetics
High-resolution genome-wide array-based comparative genome hybridization reveals cryptic chromosome changes in AML and MDS cases with trisomy 8 as the sole cytogenetic aberration
K Paulsson, M Heidenblad, B Strömbeck, J Staaf, G Jönsson, Å Borg, T Fioretos and B Johansson
Leukemia 20: 840-846; advance online publication, February 23, 2006; doi:10.1038/sj.leu.2404145
Stem Cells
Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery
J Ratajczak, K Miekus, M Kucia, J Zhang, R Reca, P Dvorak and M Z Ratajczak
Leukemia 20: 847-856; advance online publication, February 2, 2006; doi:10.1038/sj.leu.2404132
A population of very small embryonic-like (VSEL) CXCR4+SSEA-1+Oct-4+ stem cells identified in adult bone marrow
M Kucia, R Reca, F R Campbell, E Zuba-Surma, M Majka, J Ratajczak and M Z Ratajczak
Leukemia 20: 857-869; advance online publication, February 23, 2006; doi:10.1038/sj.leu.2404171
Generation and characterization of a novel hematopoietic progenitor cell line with DC differentiation potential
C Rathinam, M Sauer, A Ghosh, C Rudolph, A Hegazy, B Schlegelberger, K Welte and C Klein
Leukemia 20: 870-876; advance online publication, March 2, 2006; doi:10.1038/sj.leu.2404157
Letters to the Editor
Abnormal levels of the 
chain of the CD22 adhesion molecule may account for low CD22 surface expression in chronic lymphocytic leukemia
B Payelle-Brogard, G Dumas, C Magnac, A I Lalanne, G Dighiero and F Vuillier
Leukemia 20: 877-878; advance online publication, February 23, 2006; doi:10.1038/sj.leu.2404155
Repeats in the kringle IV encoding domains in the Apo(a) gene and serum lipoprotein(a) level do not contribute to the risk for avascular necrosis of the bone (AVN) in pediatric acute lymphoblastic leukemia
R D van Beek, D D L Bezemer, J P P Meijerink, S M P F de Muinck Keizer-Schrama, O A Haas, L te Winkel, R Pieters and M van den Heuvel-Eibrink
Leukemia 20: 879-880; advance online publication, March 9, 2006; doi:10.1038/sj.leu.2404161
Hepatotoxicity profile of single agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia, its impact on clinical outcome and the effect of genetic polymorphisms on the incidence of hepatotoxicity
V Mathews, S Desire, B George, K M Lakshmi, J G Rao, A Viswabandya, A Bajel, V M Srivastava, A Srivastava and M Chandy
Leukemia 20: 881-883; advance online publication, March 9, 2006; doi:10.1038/sj.leu.2404165
NK-cell-associated receptor expression in hepatosplenic T-cell lymphoma, insights into pathogenesis
W G Morice, W R Macon, A Dogan, C A Hanson and P J Kurtin
Leukemia 20: 883-886; advance online publication, March 9, 2006; doi:10.1038/sj.leu.2404168
Rational use of the EAC real-time quantitative PCR protocol in chronic myelogenous leukemia: report of three false-negative cases at diagnosis
B Dessars, H El Housni, F Lambert, A Kentos and P Heimann
Leukemia 20: 886-888; advance online publication, March 9, 2006; doi:10.1038/sj.leu.2404174
Immunophenotype signature as a tool to define prognostic subgroups in childhood acute myeloid leukemia
A Zangrando, A Luchini, B Buldini, R Rondelli, A Pession, S Bicciato, G te Kronnie and G Basso
Leukemia 20: 888-891; advance online publication, March 9, 2006; doi:10.1038/sj.leu.2404175
Murine model for mantle cell lymphoma
M R Smith, I Joshi, F Jin and T Al-Saleem
Leukemia 20: 891-893; advance online publication, March 9, 2006; doi:10.1038/sj.leu.2404177
Absence of pathogenic mutations of the human telomerase RNA gene (hTERC) in patients with chronic myeloproliferative disorders
S Danzy, C-y Su, S Park, S-y Li, A M Ferraris and H Ly
Leukemia 20: 893-894; advance online publication, March 2, 2006; doi:10.1038/sj.leu.2404159
Induction of CD45 expression on bone marrow-derived mesenchymal stem cells
S-P Yeh, J-G Chang, W-J Lo, Y-C Liaw, C-L Lin, C-C Lee and C-F Chiu
Leukemia 20: 894-896; advance online publication, March 9, 2006; doi:10.1038/sj.leu.2404181
Typing by nested PCR–SSP approach raises a question about the feasibility of using this technique for detecting feto-maternal microchimerism
B-S Cho, H-B Choi, H-J Kim, W-S Min, C-C Kim and T-G Kim
Leukemia 20: 896-898; advance online publication, February 23, 2006; doi:10.1038/sj.leu.2404153
Intensive chemotherapy and autologous hematopoietic stem cell mobilization, collection and transplantation with simultaneous Imatinib therapy in patients with blast crisis chronic myeloid leukaemia
D Heim, D Friess, S Christen, G Stüssi, S Meyer-Monard, A Tichelli, J R Passweg and A Gratwohl
Leukemia 20: 898-900; advance online publication, March 9, 2006; doi:10.1038/sj.leu.2404178
Endogenous TNF mediates cell survival and chemotherapy resistance by activating the PI3K/Akt pathway in acute lymphoblastic leukemia cells
L Gu, H W Findley, N Zhu and M Zhou
Leukemia 20: 900-904; advance online publication, March 2, 2006; doi:10.1038/sj.leu.2404160
Partial uniparental disomy: a recurrent genetic mechanism alternative to chromosomal deletion in malignant lymphoma
I Nielaender, J I Martín-Subero, F Wagner, J A Martínez-Climent and R Siebert
Leukemia 20: 904-905; advance online publication, March 2, 2006; doi:10.1038/sj.leu.2404173
Late first relapses in APL treated with all-trans-retinoic acid- and anthracycline- based chemotherapy: the European APL group experience (APL 91 and APL 93 trials)
C Kelaidi, L Ades, S Chevret, M Sanz, A Guerci, X Thomas, S de Botton, E Raffoux, C Rayon, N Fegueux, D Bordessoule, F Rigal-Huguet, H Link, A Stoppa, A Vekhoff, S Meyer-Monard, S Castaigne, H Dombret, L Degos and P Fenaux on behalf of the French APL group
Leukemia 20: 905-907; advance online publication, March 16, 2006; doi:10.1038/sj.leu.2404158
