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July 2002, Volume 16, Number 7

Table of Contents

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Spotlight on Signal Transduction Inhibitors: Basic Aspects and Therapeutic Implications
Molecular targets for therapy, signal transduction inhibition and imatinib FREE
N Muller-Bérat Killmann & J A McCubrey
Abstract  |  Full text  |  PDF 1205
Spotlight Imatinib: a model for signal transduction inhibitors FREE
A Hochhaus, J A McCubrey & N Muller-Bérat Killmann
Abstract  |  Full text  |  PDF 1205
Reviews
Tyrosine kinase fusion genes in chronic myeloproliferative diseases FREE
N C P Cross & A Reiter
Abstract  |  Full text  |  PDF 1207
Insights from pre-clinical studies for new combination treatment regimens with the Bcr-Abl kinase inhibitor imatinib mesylate (Gleevec/Glivec) in chronic myelogenous leukemia: a translational perspective FREE
P La Rosée, M E O'Dwyer & B J Druker
Abstract  |  Full text  |  PDF 1213
Original Manuscripts
Safety and efficacy of STI-571 (imatinib mesylate) in patients with bcr/abl-positive chronic myelogenous leukemia (CML) after autologous peripheral blood stem cell transplantation (PBSCT) FREE
T Fischer, C Reifenrath, G R Hess, M T Corsetti, S Kreil, J Beck, P Meinhardt, G Beltrami, B Schuch, H Gschaidmeier, R Hehlmann, A Hochhaus, A Carella & C Huber
Abstract  |  Full text  |  PDF 1220
Spotlight on Chronic Lymphocytic Leukemia
Chromosomal imbalances in familial chronic lymphocytic leukaemia: a comparative genomic hybridisation analysis FREE
B Summersgill, P Thornton, S Atkinson, E Matutes, J Shipley, D Catovsky, R S Houlston & M R Yuille
Abstract  |  Full text  |  PDF 1229
Antigen expression patterns reflecting genotype of acute leukemias FREE
O Hruscaronák & A Porwit-MacDonald
Abstract  |  Full text  |  PDF 1233
Induction therapy by frequent administration of doxorubicin with four other drugs, followed by intensive consolidation and maintenance therapy for adult acute lymphoblastic leukemia: the JALSG-ALL93 study FREE
J Takeuchi, T Kyo, K Naito, H Sao, M Takahashi, S Miyawaki, K Kuriyama, S Ohtake, F Yagasaki, H Murakami, N Asou, T Ino, T Okamoto, N Usui, M Nishimura, K Shinagawa, T Fukushima, H Taguchi, T Morii, S Mizuta, H Akiyama, Y Nakamura, T Ohshima & R Ohno
Abstract  |  Full text  |  PDF 1259
Deletion analysis of chromosome 13q14.3 and characterisation of an alternative splice form of LEU1 in B cell chronic lymphocytic leukemia FREE
C Rowntree, V Duke, P Panayiotidis, P Kotsi, G L Palmisano, A V Hoffbrand & L Foroni
Abstract  |  Full text  |  PDF 1267
Signals mediated by Fcbold gammaRIIA suppress the growth of B-lineage acute lymphoblastic leukemia cells FREE
T Suzuki, E Coustan-Smith, K Mihara & D Campana
Abstract  |  Full text  |  PDF 1276
Non-DNA-binding Ikaros isoform gene expressed in adult B-precursor acute lymphoblastic leukemia FREE
K Nishii, N Katayama, H Miwa, M Shikami, E Usui, M Masuya, H Araki, F Lorenzo, T Ogawa, T Kyo, K Nasu, H Shiku & K Kita
Abstract  |  Full text  |  PDF 1285
Expression pattern of HOXB6 homeobox gene in myelomonocytic differentiation and acute myeloid leukemia FREE
A Giampaolo, N Felli, D Diverio, O Morsilli, P Samoggia, M Breccia, F Lo Coco, C Peschle & U Testa
Abstract  |  Full text  |  PDF 1293
Overexpression of vascular endothelial growth factor (VEGF) and its cellular receptor KDR (VEGFR-2) in the bone marrow of patients with acute myeloid leukemia FREE
T Padró, R Bieker, S Ruiz, M Steins, S Retzlaff, H Bürger, T Büchner, T Kessler, F Herrera, J Kienast, C Müller-Tidow, H Serve, W E Berdel & R M Mesters
Abstract  |  Full text  |  PDF 1302
Early lymphocyte recovery is a predictive factor for prolonged survival after autologous hematopoietic stem cell transplantation for acute myelogenous leukemia FREE
L F Porrata, M R Litzow, A Tefferi, L Letendre, S Kumar, S M Geyer & S N Markovic
Abstract  |  Full text  |  PDF 1311
Optimized lentiviral transduction of erythroid precursors from healthy adults and patients with myelodysplastic syndromes FREE
T W Matthes, V Kindler, F Leuba, L E French, B Chapuis, P Beris & V Piguet
Abstract  |  Full text  |  PDF 1319
mRNA-electroporated mature dendritic cells retain transgene expression, phenotypical properties and stimulatory capacity after cryopreservation FREE
P Ponsaerts, V F I Van Tendeloo, N Cools, A Van Driessche, F Lardon, G Nijs, M Lenjou, G Mertens, C Van Broeckhoven, D R Van Bockstaele & Z N Berneman
Abstract  |  Full text  |  PDF 1324
Synergistic induction of mitochondrial damage and apoptosis in human leukemia cells by flavopiridol and the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) FREE
J Almenara, R Rosato & S Grant
Abstract  |  Full text  |  PDF 1331
The antifungal antibiotic clotrimazole alters calcium homeostasis of leukemic lymphoblasts and induces apoptosis FREE
C Ito, C Tecchio, E Coustan-Smith, T Suzuki, F G Behm, S C Raimondi, C-H Pui & D Campana
Abstract  |  Full text  |  PDF 1344
Haplotype study of microsatellites flanking the t(15;17) breakpoint in acute promyelocytic leukemia patients from North Portugal FREE
S Martins, F Trigo, L Azevedo, M J Silva, J E Guimaraes & A Amorim
Abstract  |  Full text  |  PDF 1353
Biased Iglambda expression in hypermutated IgD multiple myelomas does not result from receptor revision FREE
M van der Burg, R J Bende, W M Aarts, A W Langerak, J J M van Dongen & C J M van Noesel
Abstract  |  Full text  |  PDF 1358
The cholesterol lowering drug lovastatin induces cell death in myeloma plasma cells FREE
N W C J van de Donk, M M J Kamphuis, H M Lokhorst & A C Bloem
Abstract  |  Full text  |  PDF 1362
Bio-Technical Methods Section (BTS)
T cell receptor gamma gene rearrangements as targets for detection of minimal residual disease in acute lymphoblastic leukemia by real-time quantitative PCR analysis FREE
V H J van der Velden, J M Wijkhuijs, D C H Jacobs, E R van Wering & J J M van Dongen
Abstract  |  Full text  |  PDF 1372
Real-time quantitative PCR detection of WT1 gene expression in children with AML: prognostic significance, correlation with disease status and residual disease detection by flow cytometry FREE
J Trka, M Kalinová, O Hruscaronák, J Zuna, O Krejc caroní, J Mado, P Sedlác caronek, V Vávra, K Michalová, M Jaroscaronová & J Staryacute for Czech Paediatric Haematology Working Group
Abstract  |  Full text  |  PDF 1381
Spotlight Correspondence
Clonal Ph-negative hematopoiesis in CML after therapy with imatinib mesylate is frequently characterized by trisomy 8 FREE
M K Andersen, J Pedersen-Bjergaard, L Kjeldsen, I H Dufva & K Brøndum-Nielsen
Abstract  |  Full text  |  PDF 1390
ABL-specific tyrosine kinase inhibitor imatinib as salvage therapy in a child with Philadelphia chromosome-positive acute mixed lineage leukemia (AMLL) FREE
B Selle, C Bär, S Hecker, U Schmidt-Rohr, S Viehmann, K-M Debatin & D Reinhardt
Abstract  |  Full text  |  PDF 1393
Correspondence
The class II tumour suppressor gene RARRES3 maps to 11q12, not 11q23 FREE
R L Auer, F Bertoni, C Jones & F E Cotter
Abstract  |  Full text  |  PDF 1396
Response to Auer: the class II tumor-suppressor gene RARRES3 is expressed in B-CLL and down-regulated with disease progression FREE
A Garcia-Pardo
Abstract  |  Full text  |  PDF 1396
Response to Garcia-Pardo FREE
R L Auer
Abstract  |  Full text  |  PDF 1397
Reply to Auer FREE
A Garcia-Pardo
Abstract  |  Full text  |  PDF 1397
July 2002, Volume 16, Number 7
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