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| Editorial |
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| Spotlight on molecular targeted therapy: introduction FREE |
| M S Sheikh |
| Abstract | Full text | PDF |
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| 431 |
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| Spotlight on Molecular Targeted Therapy |
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| The proteasome: a novel target for cancer chemotherapy FREE |
| J B Almond & G M Cohen |
| Abstract | Full text | PDF |
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| 433 |
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| Spotlight on Molecular Targeted Therapy |
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| MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis FREE |
| R W Craig |
| Abstract | Full text | PDF |
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| 444 |
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| Spotlight on Molecular Targeted Therapy |
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| Hsp-90-associated oncoproteins: multiple targets of geldanamycin and its analogs FREE |
| M V Blagosklonny |
| Abstract | Full text | PDF |
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| 455 |
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| Spotlight on Molecular Targeted Therapy |
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| Classical and novel retinoids: their targets in cancer therapy FREE |
| J A Fontana & A K Rishi |
| Abstract | Full text | PDF |
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| 463 |
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| Spotlight on Molecular Targeted Therapy |
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| Large-scale gene expression analysis in molecular target discovery FREE |
| M S Orr & U Scherf |
| Abstract | Full text | PDF |
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| 473 |
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| Spotlight on Molecular Targeted Therapy |
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| Identification of novel targets for cancer therapy using expression proteomics FREE |
| S M Hanash, J Madoz-Gurpide & D E Misek |
| Abstract | Full text | PDF |
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| 478 |
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| Spotlight on Molecular Targeted Therapy |
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| The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia FREE |
| J T Lee Jr & J A McCubrey |
| Abstract | Full text | PDF |
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| 486 |
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| Spotlight on Molecular Targeted Therapy |
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| HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis FREE |
| W W-L Wong, J Dimitroulakos, M D Minden & L Z Penn |
| Abstract | Full text | PDF |
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| 508 |
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| Spotlight on Molecular Targeted Therapy |
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| Developmental Therapeutics Program at the NCI: molecular target and drug discovery process FREE |
| M Monga & E A Sausville |
| Abstract | Full text | PDF |
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| 520 |
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| Spotlight on Molecular Targeted Therapy |
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| Myeloid Differentiation (MyD)/Growth Arrest DNA Damage (GADD) genes in tumor suppression, immunity and inflammation FREE |
| D A Liebermann & B Hoffman |
| Abstract | Full text | PDF |
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| 527 |
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| Spotlight on Stem Cells |
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| Toward a new paradigm of cell plasticity FREE |
| N D Theise & D S Krause |
| Abstract | Full text | PDF |
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| 542 |
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| Spotlight on Stem Cells |
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| Elucidating critical mechanisms of deregulated stem cell turnover in the chronic phase of chronic myeloid leukemia FREE |
| T L Holyoake, X Jiang, M W Drummond, A C Eaves & C J Eaves |
| Abstract | Full text | PDF |
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| 549 |
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| Spotlight on Stem Cells |
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| Unique molecular and cellular features of acute myelogenous leukemia stem cells FREE |
| C T Jordan |
| Abstract | Full text | PDF |
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| 559 |
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| Spotlight on Stem Cells |
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| Development of gene therapy for hematopoietic stem cells using lentiviral vectors FREE |
| N-B Woods, A Ooka & S Karlsson |
| Abstract | Full text | PDF |
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| 563 |
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| Mini-Review |
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| STI-571 must select for drug-resistant cells but 'no cell breathes fire out of its nostrils like a dragon' FREE |
| M V Blagosklonny |
| Abstract | Full text | PDF |
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| 570 |
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| Original Manuscripts |
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Results of a phase II trial of a combination of oral cytarabine ocfosfate (YNK01) and interferon  -2b for the treatment of chronic myelogenous leukemia patients in chronic phase FREE |
| F Maloisel, A Guerci, D Guyotat, N Ifrah, M Michallet, J Reiffers, G Tertain, M Blanc, F Bauduer, J Brière, J F Abgrall, B Pegourie-Bandelier, E Solary, N Cambier, D Coso, J P Vilque, M Delain, J L Harousseau, P Rousselot, K Belhadj, P Morice, J Attal, M Chabin, C Chastang, J Guilhot & F Guilhot for France Intergroupe des Leucémies Myéloïdes Chroniques |
| Abstract | Full text | PDF |
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| 573 |
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| Less intense conditioning with fludarabine, cyclophosphamide, idarubicin and etoposide (FCIE) followed by allogeneic unselected peripheral blood stem cell transplantation in elderly patients with leukemia FREE |
| R F Schlenk, F Hartmann, M Hensel, W Jung, R Weber-Nordt, A Gabler, R Haas, A D Ho, L Trümper & H Döhner |
| Abstract | Full text | PDF |
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| 581 |
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| Sequential chemotherapy by CHOP and DHAP regimens followed by high-dose therapy with stem cell transplantation induces a high rate of complete response and improves event-free survival in mantle cell lymphoma: a prospective study FREE |
| F Lefrère, A Delmer, F Suzan, V Levy, C Belanger, M Djabarri, B Arnulf, G Damaj, N Maillard, V Ribrag, M Janvier, C Sebban, R-O Casasnovas, R Bouabdallah, F Dreyfus, V Verkarre, E Delabesse, F Valensi, E McIntyre, N Brousse, B Varet & O Hermine |
| Abstract | Full text | PDF |
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| 587 |
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| Long-term follow-up of short intensive multiagent chemotherapy without high-dose methotrexate ('Orange') in children with advanced non-lymphoblastic non-Hodgkin's lymphoma: a Children's Cancer Group Report FREE |
| M S Cairo, M D Krailo, M Morse, R J Hutchinson, R E Harris, C R Kjeldsberg, M E Kadin, E Radel, L J Steinherz, E Morris, J L Finlay & A T Meadows |
| Abstract | Full text | PDF |
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| 594 |
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| Prognostic variables in newly diagnosed children and adolescents with acute myeloid leukemia: Children's Cancer Group Study 213 FREE |
| R J Wells, D C Arthur, A Srivastava, N A Heerema, M Le Beau, T A Alonzo, A B Buxton, W G Woods, W B Howells, D R Benjamin, D L Betcher, J D Buckley, S A Feig, T Kim, L F Odom, F B Ruymann, W A Smithson, R Tannous, J K Whitt, L Wolff, T Tjoa & B C Lampkin |
| Abstract | Full text | PDF |
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| 601 |
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| Plant stress hormones suppress the proliferation and induce apoptosis in human cancer cells FREE |
| O Fingrut & E Flescher |
| Abstract | Full text | PDF |
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| 608 |
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| Arsenic trioxide therapy for relapsed or refractory Japanese patients with acute promyelocytic leukemia: need for careful electrocardiogram monitoring FREE |
| K Ohnishi, H Yoshida, K Shigeno, S Nakamura, S Fujisawa, K Naito, K Shinjo, Y Fujita, H Matsui, N Sahara, A Takeshita, H Satoh, H Terada & R Ohno |
| Abstract | Full text | PDF |
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| 617 |
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| Primary myelodysplasia occurring in adults under 50 years old: a clinicopathologic study of 52 patients FREE |
| K L Chang, M R O'Donnell, M L Slovak, A C Dagis, D A Arber, J C Niland & S J Forman |
| Abstract | Full text | PDF |
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| 623 |
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| Significance of the levels of bone marrow lymphoid infiltrate in chronic lymphocytic leukemia patients with nodular partial remission FREE |
| R Oudat, M J Keating, S Lerner, S O'Brien & M Albitar |
| Abstract | Full text | PDF |
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| 632 |
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| Immunoglobulin diversification in B cell malignancies: internal splicing of heavy chain variable region as a by-product of somatic hypermutation FREE |
| R J Bende, W M Aarts, S T Pals & C J M van Noesel |
| Abstract | Full text | PDF |
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| 636 |
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| Allogeneic hematopoietic stem cell transplantation for 27 children with juvenile myelomonocytic leukemia diagnosed based on the criteria of the International JMML Working Group FREE |
| A Manabe, J Okamura, K Yumura-Yagi, Y Akiyama, M Sako, H Uchiyama, S Kojima, K Koike, T Saito & T Nakahata for the MDS Committee of the Japanese Society of Pediatric Hematology |
| Abstract | Full text | PDF |
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| 645 |
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| Migratory behavior of leukemic cells from acute myeloid leukemia patients FREE |
| C Voermans, W P M van Heese, I de Jong, W R Gerritsen & C E van der Schoot |
| Abstract | Full text | PDF |
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| 650 |
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| AML1 gene over-expression in childhood acute lymphoblastic leukemia FREE |
| F M Mikhail, K A Serry, N Hatem, Z I Mourad, H M Farawela, D M El Kaffash, L Coignet & G Nucifora |
| Abstract | Full text | PDF |
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| 658 |
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| ETV6/AML1 fusion by FISH in adult acute lymphoblastic leukemia FREE |
| M S Jabber Al-Obaidi, M Martineau, C F Bennett, I M Franklin, A H Goldstone, L Harewood, G R Jalali, H G Prentice, S M Richards, K Roberts & C J Harrison on behalf of the Medical Research Council Adult Leukaemia Working Party |
| Abstract | Full text | PDF |
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| 669 |
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Downregulation of IL-6-induced STAT3 tyrosine phosphorylation by TGF- 1 is mediated by caspase-dependent and -independent processes FREE |
| A T J Wierenga, J J Schuringa, B J L Eggen, W Kruijer & E Vellenga |
| Abstract | Full text | PDF |
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| 675 |
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| Importance of MEK-1/-2 signaling in monocytic and granulocytic differentiation of myeloid cell lines FREE |
| M B Miranda, T F McGuire & D E Johnson |
| Abstract | Full text | PDF |
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| 683 |
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| Analysis of CD20-dependent cellular cytotoxicity by G-CSF-stimulated neutrophils FREE |
| L E van der Kolk, M de Haas, A J Grillo-López, J W Baars & M H J van Oers |
| Abstract | Full text | PDF |
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| 693 |
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| T and B leukemic cell lines exhibit different requirements for cell death: correlation between caspase activation, DFF40/DFF45 expression, DNA fragmentation and apoptosis in T cell lines but not in Burkitt's lymphoma FREE |
| F Luciano, J-E Ricci, M Herrant, C Bertolotto, B Mari, J-L Cousin & P Auberger |
| Abstract | Full text | PDF |
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| 700 |
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| Nitric oxide induces the apoptosis of human BCR-ABL-positive myeloid leukemia cells: evidence for the chelation of intracellular iron FREE |
| H Ferry-Dumazet, M Mamani-Matsuda, M Dupouy, F Belloc, D Thiolat, G Marit, M Arock, J Reiffers & M D Mossalayi |
| Abstract | Full text | PDF |
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| 708 |
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| Antibody status to HHV-6 in children with leukaemia FREE |
| M J H Salonen, M A Siimes, E-M Salonen, A Vaheri & M Koskiniemi |
| Abstract | Full text | PDF |
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| 716 |
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| Acute lymphoblastic leukemia incidence during socioeconomic transition: selective increase in children from 1 to 4 years FREE |
O Hru ák, J Trka, J Zuna, A Polou ková, T Kalina & J Star for Czech Pediatric Hematology Working Group |
| Abstract | Full text | PDF |
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| 720 |
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| Relationship between expression of genes involved in cell cycle control and apoptosis in diffuse large B cell lymphoma: a preferential survivin-cyclin B link FREE |
| F Kuttler, M-B Valnet-Rabier, R Angonin, C Ferrand, E Deconinck, C Mougin, J-Y Cahn & T Fest |
| Abstract | Full text | PDF |
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| 726 |
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| Keynote Address |
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| Immunologic manipulation in AML: from bench to bedside FREE |
| M A Cooper & M A Caligiuri |
| Abstract | Full text | PDF |
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| 736 |
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| Keynote Address |
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| Mpl and the hematopoietic stem cell FREE |
| K Kaushansky |
| Abstract | Full text | PDF |
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| 738 |
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| Keynote Address |
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| Cooperativity between mutations in tyrosine kinases and in hematopoietic transcription factors in AML FREE |
| K Deguchi & D G Gilliland |
| Abstract | Full text | PDF |
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| 740 |
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| Keynote Address |
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| Postremission therapy in older adults with acute myeloid leukemia: an opportunity for new drug development FREE |
| C A Schiffer |
| Abstract | Full text | PDF |
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| 745 |
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| Keynote Address |
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| Therapy of secondary leukemia FREE |
| J M Rowe |
| Abstract | Full text | PDF |
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| 748 |
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| Keynote Address |
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| Long-term outcome of allogeneic transplants in acute myeloid leukemia FREE |
| H A Messner |
| Abstract | Full text | PDF |
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| 751 |
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| Keynote Address |
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| Mixed allogeneic chimerism and graft-versus-leukemia effects in acute myeloid leukemia FREE |
| R Storb |
| Abstract | Full text | PDF |
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| 753 |
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| Biotechnical Methods Section (BTS) |
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| A single split-signal FISH probe set allows detection of TAL1translocations as well as SIL-TAL1 fusion genes in a single test FREE |
| M van der Burg, B Smit, B Brinkhof, B H Barendregt, M C M Verschuren, M Dib, H B Beverloo, J J M van Dongen & A W Langerak |
| Abstract | Full text | PDF |
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| 755 |
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| Correspondence |
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| A competitive PCR-based method using TCRD, TCRG and IGH rearrangements for rapid detection of patients with high levels of minimal residual disease in acute lymphoblastic leukemia FREE |
| C Guidal, E Vilmer, B Grandchamp & H Cavé |
| Abstract | Full text | PDF |
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| 762 |
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| Polymorphisms in methylenetetrahydrofolate reductase and methotrexate sensitivity in childhood acute lymphoblastic leukemia FREE |
| J W Taub, L H Matherly, Y Ravindranath, G-J L Kaspers, M G Rots & C H Zantwijk |
| Abstract | Full text | PDF |
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| 764 |
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| April 2002, Volume 16, Number 4 |
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