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Volume 52 Issue 8, August 2023

New calculator for planning breedings

Colony management of gene-modified animals is time-consuming, costly and affected by random events related to Mendelian genetics, fertility and litter size. In a new Article, Milchevskaya, Bugnon et al. developed an R package that enables the estimation of group size required for mouse breeding, taking into account Mendelian genetics, fertility and litter size.

See Milchevskaya, Bugnon et al.

Numbers image: Pashabo / iStock / Getty Images Plus. Illustration and cover design: Marina Spence

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  • Sharing research tools and data with other scientists brings many benefits, such as using fewer animals, improving reproducibility and increasing study sample size, but the practice still needs to be more widely adopted.

    • Charlotte Harrison
    Technology Feature
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