Volume 52 Issue 2, February 2023

Egr2 regulates mouse social and cooperative behaviors

Social isolation is known to alter social behaviors in mice, but the underlying mechanisms are unclear. In a new article, Zhang et al. identify early growth response 2 (Egr2/Krox-20) in the medial prefrontal cortex as a major target of social isolation and resocialization, and uncover its critical role in the development mouse social and cooperative behaviors.

See Zhang et al.

COVER IMAGE: Marina Spence. COVER DESIGN: Marina Spence.