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Volume 51 Issue 7, July 2022

The genomic landscape of canine diffuse large B-cell lymphoma

Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoid neoplasm in dogs and in humans. In a new article, Giannuzzi and colleagues performed an integrated analysis of clinical features, exome and RNA sequencing data in a cohort of dogs with DLBCL to better define the genetic landscape of this tumor and identify potential therapeutic targets.

See Giannuzzi et al.

COVER IMAGE: Marina Spence. COVER DESIGN: Marina Spence.

Volume 51 Issue 7

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  • Single nucleotide polymorphisms in the FKBP5 gene influence the risk of developing stress-related disorders, but the underlying processes are not fully understood. Animal models offer a possibility to investigate the influence of FKBP5 gene variants on the stress response system.

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