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Zebrafish will learn to fear an aversive stimulus. That stimulus, however, need not be pain, nor involve conspecifics. Robotic replicas that mimic zebrafish—a trio of which are depicted on the cover illustration and deployed in a new Research Article—can do the trick.
The refined fear-conditioning paradigm may prove useful in behavioural pharmacology, allowing researchers to take advantage of the high-throughput potential of zebrafish to explore the effects of aversive experiences and test potential therapeutics.
Robyn Raban and Omar Akbari describe a day in the life of the mosquito insectary team at the University of California, San Diego, outlining the procedures, goals, and types of systems they are engineering to control mosquito-transmitted diseases.
There’s growing evidence that sex-based differences can influence phenotypes beyond those directly related to the reproductive system; to fully understand a gene’s function, researchers should consider both male and female subjects.
Here, the authors present a new fear-conditioning paradigm in zebrafish using a robotic platform composed of three zebrafish replicas as a fear-eliciting stimulus.