Volume 49 Issue 4, April 2020

Rehabilitation of tumor-afflicted sea turtles, and their utilization as a natural model for human and wildlife cancers.

Personalizing zebrafish and fly models may help determine the best course of treatment for cancer patients.

Human cancer is a disease of cooperating genetic events that is complex to model in vivo. A new study combines somatic base editing with a mouse model of breast cancer, demonstrating the potential to rapidly investigate the function of disease-specific point mutations.

In rats, forced running wheel exercise activates an adaptation of the antioxidant system response in skeletal muscle at speeds <16 m/min, whereas it induces oxidative stress at higher speeds in muscle, liver and serum.