Immunoglobulin and T cell receptor (TCR) germline transcription is associated with V(D)J recombination of these loci. New work formally demonstrates that transcriptional read-through of the TCR–Jα cluster indeed regulates TCR-Jα rearrangements.
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Kim Caesar
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de Villartay, JP. Passera ou ne passera pas—accessibility is key. Nat Immunol 7, 1019–1021 (2006). https://doi.org/10.1038/ni1006-1019
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DOI: https://doi.org/10.1038/ni1006-1019
