The innate inflammatory immune response must be finely tuned to avoid excessive damage to the host. One molecule, A20, is intricately involved in dampening inflammatory signals mediated by both tumor necrosis factor and multiple Toll-like receptors.
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Silverman, N., Fitzgerald, K. DUBbing down innate immunity. Nat Immunol 5, 1010–1012 (2004). https://doi.org/10.1038/ni1004-1010
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DOI: https://doi.org/10.1038/ni1004-1010
