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GPCR dimers moving closer

Time-resolved fluorescence resonance energy transfer (TR-FRET) measurements with selective, fluorescently labeled ligands support the existence of GPCR dimers in native tissues and suggest that activated GPCR dimers are asymmetric.

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Correspondence to Martin J Lohse.

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Ambrosio, M., Lohse, M. GPCR dimers moving closer. Nat Chem Biol 6, 570–571 (2010). https://doi.org/10.1038/nchembio.409

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