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Focus on Biomolecular Tailoring

Nucleic acids, proteins and other biological macromolecules undergo chemical tailoring reactions during their biosynthesis and as they execute their biological functions. In our March 2018 issue, Nature Chemical Biology highlights several classes of post-translational modifications of proteins, as well as chemical modifications of nucleic acids, lipids, and carbohydrates, and explores the role of chemical biology in understanding the structural diversity and functional roles of these important biomolecules.

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