Microscopic Imaging in Deep Tissue

Obtaining clearer and more detailed microscopic images deep within tissue has become a rich area of research in fields ranging from adaptive optics to photodynamic therapy. Visualising biological structures in vivo or non-invasively is a powerful strategy for discoveries in the live workings of our cells, tissues and organs. However, breaking the technological and biological barriers that traditionally limit imaging in deep tissue to the range of a few millimeters requires exceptional techniques and pioneering research developments.

Nature Communications, Communications Biology, Communications Engineering, npj Imaging and Scientific Reports are now inviting research Articles on the topic of microscopic imaging within deep tissue. This Collection will highlight Articles that involve new tools and emerging techniques for imaging at increased penetration depths within tissue as well as considering advances in conventional and state-of-the-art light microscopy techniques.

Topics of interest include but are not limited to: tools and techniques for microscopy in deep tissue, multimodal solutions for increasing penetration depth, and advancements in image processing. Reviews, Perspectives, and Comments covering these topics will also be considered for inclusion in the Collection. All submissions will be subject to the same review process and editorial standards as regular articles submitted to the contributing journals.