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Immunoglobulin Expression and Its Biological Significance in Cancer Cells

Cellular & Molecular Immunology volume 5, pages 319–324 (2008)Cite this article

Abstract

It is generally believed that the expression of a gene is restricted “within the right place and at the right time”. This principle has long been considered applicable as well to the expression of immunoglobulin (Ig) lymphocytes of B cell lineage. However, increasing evidence has shown Ig “paradoxically” expressed in malignant tumors of epithelial origin. We reviewed the recent progress in the study of cancer-derived Ig, and also discussed its mechanisms and possible functions, trying to arouse interest and attention to those working in the field of immunology and oncology.

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Author notes

  1. Duosha Hu and Hui Zheng: These two author contributed equally to this paper

Authors and Affiliations

  1. Cancer Research Institute, Xiangya School of Medicine, Central South University, Changsha, Hunan, China

    Duosha Hu, Hui Zheng, Haidan Liu, Ming Li, Wei Ren, Wei Liao, Zhi Duan, Lili Li & Ya Cao

Authors
  1. Duosha Hu
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  2. Hui Zheng
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  3. Haidan Liu
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  4. Ming Li
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  5. Wei Ren
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  6. Wei Liao
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  7. Zhi Duan
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  8. Lili Li
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  9. Ya Cao
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Corresponding author

Correspondence to Ya Cao.

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Hu, D., Zheng, H., Liu, H. et al. Immunoglobulin Expression and Its Biological Significance in Cancer Cells. Cell Mol Immunol 5, 319–324 (2008). https://doi.org/10.1038/cmi.2008.39

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  • DOI: https://doi.org/10.1038/cmi.2008.39

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