Table of contents

Volume 99, Issue 8
Published online 14 October 2008 (1197-1368)

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Minireviews

mTORC1 inhibitors: is temsirolimus in renal cancer telling us how they really work? FREE

C Le Tourneau, S Faivre, M Serova and E Raymond

Br J Cancer 99: 1197-1203; advance online publication, September 16, 2008; doi:10.1038/sj.bjc.6604636

VEGF and Delta-Notch: interacting signalling pathways in tumour angiogenesis FREE

G Thurston and J Kitajewski

Br J Cancer 99: 1204-1209; advance online publication, September 30, 2008; doi:10.1038/sj.bjc.6604484

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Clinical Studies

Endometrial stromal sarcoma: a population-based analysis FREE

J K Chan, N M Kawar, J Y Shin, K Osann, L-m Chen, C B Powell and D S Kapp

Br J Cancer 99: 1210-1215; advance online publication, September 23, 2008; doi:10.1038/sj.bjc.6604527

Adjuvant hysterectomy for treatment of residual disease in patients with cervical cancer treated with radiation therapy FREE

T Ota, N Takeshima, T Tabata, K Hasumi and K Takizawa

Br J Cancer 99: 1216-1220; doi:10.1038/sj.bjc.6604619

Breast cancer awareness among older women FREE

L Linsell, C C Burgess and A J Ramirez

Br J Cancer 99: 1221-1225; advance online publication, September 23, 2008; doi:10.1038/sj.bjc.6604668

NEAT: National Epirubicin Adjuvant Trial – toxicity, delivered dose intensity and quality of life FREE

H M Earl, L Hiller, J A Dunn, S Bathers, P Harvey, A Stanley, R J Grieve, R K Agrawal, I N Fernando, A M Brunt, K McAdam, S O'Reilly, D W Rea, D Spooner and C J Poole on behalf of the NEAT Investigators

Br J Cancer 99: 1226-1231; advance online publication, September 16, 2008; doi:10.1038/sj.bjc.6604674

Cost-effectiveness of adjuvant chemotherapy with uracil–tegafur for curatively resected stage III rectal cancer FREE

A Hisashige, S Yoshida and S Kodaira

Br J Cancer 99: 1232-1238; advance online publication, September 16, 2008; doi:10.1038/sj.bjc.6604666

Pharmacokinetic and pharmacogenetic determinants of the activity and toxicity of irinotecan in metastatic colorectal cancer patients FREE

E Rouits, V Charasson, A Pétain, M Boisdron-Celle, J-P Delord, M Fonck, A Laurand, A-L Poirier, A Morel, E Chatelut, J Robert and E Gamelin

Br J Cancer 99: 1239-1245; advance online publication, September 16, 2008; doi:10.1038/sj.bjc.6604673

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Translational Therapeutics

Adiponectin differentially affects gene expression in human mammary epithelial and breast cancer cells FREE

O Treeck, C Lattrich, I Juhasz-Boess, S Buchholz, G Pfeiler and O Ortmann

Br J Cancer 99: 1246-1250; advance online publication, September 30, 2008; doi:10.1038/sj.bjc.6604692

CYP2C19 pharmacogenetics in advanced cancer: compromised function independent of genotype FREE

N A Helsby, W-Y Lo, K Sharples, G Riley, M Murray, K Spells, M Dzhelai, A Simpson and M Findlay

Br J Cancer 99: 1251-1255; doi:10.1038/sj.bjc.6604699

Liposomal encapsulation enhances the antitumour efficacy of the vascular disrupting agent ZD6126 in murine B16.F10 melanoma FREE

M H A M Fens, K J Hill, J Issa, S E Ashton, F R Westwood, D C Blakey, G Storm, A J Ryan and R M Schiffelers

Br J Cancer 99: 1256-1264; advance online publication, September 16, 2008; doi:10.1038/sj.bjc.6604675

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Molecular Diagnostics

A novel AKT3 mutation in melanoma tumours and cell lines FREE

M A Davies, K Stemke-Hale, C Tellez, T L Calderone, W Deng, V G Prieto, A J F Lazar, J E Gershenwald and G B Mills

Br J Cancer 99: 1265-1268; advance online publication, September 23, 2008; doi:10.1038/sj.bjc.6604637

C-Fos expression is a molecular predictor of progression and survival in epithelial ovarian carcinoma FREE

S Mahner, C Baasch, J Schwarz, S Hein, L Wölber, F Jänicke and K Milde-Langosch

Br J Cancer 99: 1269-1275; doi:10.1038/sj.bjc.6604650

PTCH mutations in basal cell carcinomas from azathioprine-treated organ transplant recipients FREE

C A Harwood, N R Attard, P O'Donovan, P Chambers, C M Perrett, C M Proby, J M McGregor and P Karran

Br J Cancer 99: 1276-1284; doi:10.1038/sj.bjc.6604665

CD133 expression is an independent prognostic marker for low survival in colorectal cancer FREE

D Horst, L Kriegl, J Engel, T Kirchner and A Jung

Br J Cancer 99: 1285-1289; advance online publication, September 9, 2008; doi:10.1038/sj.bjc.6604664

High expression of TROP2 correlates with poor prognosis in pancreatic cancer FREE

D Fong, P Moser, C Krammel, J M Gostner, R Margreiter, M Mitterer, G Gastl and G Spizzo

Br J Cancer 99: 1290-1295; advance online publication, September 23, 2008; doi:10.1038/sj.bjc.6604677

Is PTEN loss associated with clinical outcome measures in human prostate cancer? FREE

P McCall, C J Witton, S Grimsley, K V Nielsen and J Edwards

Br J Cancer 99: 1296-1301; doi:10.1038/sj.bjc.6604680

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Genetics and Genomics

In vitro phosphorylation of BRCA2 by the checkpoint kinase CHEK2 FREE

S Kim, G Mohapatra and D A Haber

Br J Cancer 99: 1302-1306; advance online publication, September 16, 2008; doi:10.1038/sj.bjc.6604644

Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis FREE

A Takeno, I Takemasa, Y Doki, M Yamasaki, H Miyata, S Takiguchi, Y Fujiwara, K Matsubara and M Monden

Br J Cancer 99: 1307-1315; advance online publication, September 30, 2008; doi:10.1038/sj.bjc.6604682

GSTP1 Ile105Val polymorphism correlates with progression-free survival in MCRC patients treated with or without irinotecan: a study of the Dutch Colorectal Cancer Group FREE

D M Kweekel, M Koopman, N F Antonini, T Van der Straaten, J W R Nortier, H Gelderblom, C J A Punt and H-J Guchelaar

Br J Cancer 99: 1316-1321; advance online publication, September 16, 2008; doi:10.1038/sj.bjc.6604654

NET1-mediated RhoA activation facilitates lysophosphatidic acid-induced cell migration and invasion in gastric cancer FREE

D Murray, G Horgan, P MacMathuna and P Doran

Br J Cancer 99: 1322-1329; advance online publication, September 30, 2008; doi:10.1038/sj.bjc.6604688

Identification of novel neuroendocrine-specific tumour genes FREE

E Hofsli, T E Wheeler, M Langaas, A Lægreid and L Thommesen

Br J Cancer 99: 1330-1339; advance online publication, September 30, 2008; doi:10.1038/sj.bjc.6604565

Case–control study and meta-analysis of SULT1A1 Arg213His polymorphism for gene, ethnicity and environment interaction for cancer risk FREE

A Kotnis, S Kannan, R Sarin and R Mulherkar

Br J Cancer 99: 1340-1347; doi:10.1038/sj.bjc.6604683

Hypoxia upregulates expression of human endosialin gene via hypoxia-inducible factor 2 FREE

A Ohradanova, K Gradin, M Barathova, M Zatovicova, T Holotnakova, J Kopacek, S Parkkila, L Poellinger, S Pastorekova and J Pastorek

Br J Cancer 99: 1348-1356; advance online publication, September 23, 2008; doi:10.1038/sj.bjc.6604685

TGF-beta1 genotype and phenotype in breast cancer and their associations with IGFs and patient survival FREE

L Mu, D Katsaros, L Lu, M Preti, A Durando, R Arisio and H Yu

Br J Cancer 99: 1357-1363; advance online publication, September 30, 2008; doi:10.1038/sj.bjc.6604689

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Letters to the Editor

Clinical outcome and prognostic factors for patients treated within the context of a phase I study: the Royal Marsden Hospital experience FREE

U Tirelli

Br J Cancer 99: 1364; advance online publication, September 9, 2008; doi:10.1038/sj.bjc.6604648

Reply: Clinical outcome and prognostic factors for patients treated within a phase I study: the Royal Marsden Hospital Experience FREE

D Olmos, H-T Arkenau, J E Ang, J S de Bono, I Judson and S B Kaye

Br J Cancer 99: 1365; doi:10.1038/sj.bjc.6604649

Faecal tumour pyruvate kinase M2: not a good marker for the detection of colorectal adenomas FREE

Y M Shastri and J M Stein

Br J Cancer 99: 1366; advance online publication, September 30, 2008; doi:10.1038/sj.bjc.6604656

Reply: Faecal tumour pyruvate kinase M2: not a good marker for detection of colorectal adenomas FREE

U Haug, S Hundt and H Brenner

Br J Cancer 99: 1367; advance online publication, September 30, 2008; doi:10.1038/sj.bjc.6604679

Resistance to chemotherapy FREE

J Hofmann

Br J Cancer 99: 1368; advance online publication, September 9, 2008; doi:10.1038/sj.bjc.6604663

The published online date indicates the date that the issue is published online and is the first official publication date of the issue. Each print issue of BJC is published one week after it has been published online.

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