Table of contents

Volume 89, Issue 6
Published online 9 September 2003 (957-1145)

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Editorial

Trials and tribulations: obstacles to clinical trial recruitment FREE

N Reed and N Siddiqui

Br J Cancer 89: 957-958; doi:10.1038/sj.bjc.6601233

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Review

The role of HER-2/neu expression on the survival of patients with lung cancer: a systematic review of the literature FREE

A-P Meert, B Martin, M Paesmans, T Berghmans, C Mascaux, J-M Verdebout, P Delmotte, J-J Lafitte and J-P Sculier

Br J Cancer 89: 959-965; doi:10.1038/sj.bjc.6601252

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Clinical

Is optimal first-line chemotherapy deliverable in all newly diagnosed ovarian cancers? A population-based study FREE

O M McNally, E Delaney, R D Petty, M E Cruickshank, A W Hutcheon and D E Parkin

Br J Cancer 89: 966-967; doi:10.1038/sj.bjc.6601071

Intermittent chemotherapy in metastatic androgen-independent prostate cancer FREE

T M Beer, M Garzotto, W D Henner, K M Eilers and E M Wersinger

Br J Cancer 89: 968-970; doi:10.1038/sj.bjc.6601232

Androgen deprivation and cognition in prostate cancer FREE

E Salminen, R Portin, J Korpela, H Backman, L-M Parvinen, H Helenius and M Nurmi

Br J Cancer 89: 971-976; doi:10.1038/sj.bjc.6601235

Pretreatment haemoglobin levels significantly predict the tumour response to primary chemotherapy in human breast cancer FREE

A Bottini, A Berruti, M P Brizzi, A Bersiga, D Generali, G Allevi, S Aguggini, G Bolsi, S Bonardi, G Bertoli, P Alquati and L Dogliotti

Br J Cancer 89: 977-982; doi:10.1038/sj.bjc.6601216

Her-2/neu-triggered intracellular tyrosine kinase activation: in vivo relevance of ligand-independent activation mechanisms and impact upon the efficacy of trastuzumab-based treatment FREE

G Hudelist, W J Köstler, J Attems, K Czerwenka, R Müller, M Manavi, G G Steger, E Kubista, C C Zielinski and C F Singer

Br J Cancer 89: 983-991; doi:10.1038/sj.bjc.6601160

Irinotecan plus leucovorin-modulated 5-fluorouracil I.V. bolus every other week may be a suitable therapeutic option also for elderly patients with metastatic colorectal carcinoma FREE

P Comella, A Farris, V Lorusso, S Palmeri, L Maiorino, L De Lucia, F Buzzi, S Mancarella, F De Vita and A Gambardella

Br J Cancer 89: 992-996; doi:10.1038/sj.bjc.6601214

Irinotecan is active in chemonaive patients with metastatic gastric cancer: a phase II multicentric trial FREE

C-H Köhne, R Catane, B Klein, M Ducreux, P Thuss-Patience, N Niederle, M Gips, P Preusser, A Knuth, M Clemens, R Bugat, I Figer, A Shani, B Fages, D Di Betta, C Jacques and H J Wilke

Br J Cancer 89: 997-1001; doi:10.1038/sj.bjc.6601226

Cost-minimisation analysis of pegylated liposomal doxorubicin hydrochloride versus topotecan in the treatment of patients with recurrent epithelial ovarian cancer in Spain FREE

B Ojeda, L M de Sande, A Casado, P Merino and M A Casado

Br J Cancer 89: 1002-1007; doi:10.1038/sj.bjc.6601228

Phase II study of cisplatin, ifosfamide, and irinotecan with rhG-CSF support in patients with stage IIIb and IV non-small-cell lung cancer FREE

A Fujita, T Ohkubo, H Hoshino, H Takabatake, S Tagaki, K Sekine and S Abe

Br J Cancer 89: 1008-1012; doi:10.1038/sj.bjc.6601230

Supportive care in patients with advanced non-small-cell lung cancer FREE

M Di Maio, F Perrone, C Gallo, R V Iaffaioli, L Manzione, F V Piantedosi, S Cigolari, A Illiano, S Barbera, S F Robbiati, E Piazza, G P Ianniello, L Frontini, E Veltri, F Castiglione, F Rosetti, E De Maio, P Maione and C Gridelli

Br J Cancer 89: 1013-1021; doi:10.1038/sj.bjc.6601236

Performance status score: do patients and their oncologists agree? FREE

S P Blagden, S C Charman, L D Sharples, L R A Magee and D Gilligan

Br J Cancer 89: 1022-1027; doi:10.1038/sj.bjc.6601231

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Molecular and Cellular Pathology

Evaluation of cumulative prognostic scores based on the systemic inflammatory response in patients with inoperable non-small-cell lung cancer FREE

L M Forrest, D C McMillan, C S McArdle, W J Angerson and D J Dunlop

Br J Cancer 89: 1028-1030; doi:10.1038/sj.bjc.6601242

Glomeruloid microvascular proliferation is associated with p53 expression, germline BRCA1 mutations and an adverse outcome following breast cancer FREE

J R Goffin, O Straume, P O Chappuis, J-S Brunet, L R Bégin, N Hamel, N Wong, L A Akslen and W D Foulkes

Br J Cancer 89: 1031-1034; doi:10.1038/sj.bjc.6601195

Early changes in apoptosis and proliferation following primary chemotherapy for breast cancer FREE

C D Archer, M Parton, I E Smith, P A Ellis, J Salter, S Ashley, G Gui, N Sacks, S R Ebbs, W Allum, N Nasiri and M Dowsett

Br J Cancer 89: 1035-1041; doi:10.1038/sj.bjc.6601173

Overexpression of hypoxia-inducible-factor 1alpha(HIF-1alpha) in oesophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage FREE

T Kurokawa, M Miyamoto, K Kato, Y Cho, Y Kawarada, Y Hida, T Shinohara, T Itoh, S Okushiba, S Kondo and H Katoh

Br J Cancer 89: 1042-1047; doi:10.1038/sj.bjc.6601186

Aberrant expression of minichromosome maintenance protein-2 and Ki67 in laryngeal squamous epithelial lesions FREE

P Chatrath, I S Scott, L S Morris, R J Davies, S M Rushbrook, K Bird, S L Vowler, J W Grant, I T Saeed, D Howard, R A Laskey and N Coleman

Br J Cancer 89: 1048-1054; doi:10.1038/sj.bjc.6601234

Cytotoxic T-cell precursor frequencies to HER-2 (369 – 377) in patients with HER-2/neu-positive epithelial tumours FREE

P A Sotiropoulou, S A Perez, E G Iliopoulou, I Missitzis, V Voelter, H Echner, C N Baxevanis and M Papamichail

Br J Cancer 89: 1055-1061; doi:10.1038/sj.bjc.6601244

HPV infection and number of lifetime sexual partners are strong predictors for 'natural' regression of CIN 2 and 3 FREE

J K Chan, B J Monk, C Brewer, K A Keefe, K Osann, S McMeekin, G S Rose, M Youssef, S P Wilczynski, F L Meyskens and M L Berman

Br J Cancer 89: 1062-1066; doi:10.1038/sj.bjc.6601196

Soluble form of carbonic anhydrase IX (CA IX) in the serum and urine of renal carcinoma patients FREE

J Závada, Z Závadová, M Zat'ovic caronová, L Hyrs caronl and I Kawaciuk

Br J Cancer 89: 1067-1071; doi:10.1038/sj.bjc.6601264

The melanocyte inducing factor MITF is stably expressed in cell lines from human clear cell sarcoma FREE

K K C Li, J Goodall, C R Goding, S-K Liao, C-H Wang, Y-C Lin, H Hiraga, T Nojima, K Nagashima, K-L Schaefer and K A W Lee

Br J Cancer 89: 1072-1078; doi:10.1038/sj.bjc.6601212

Heat shock cognate protein 70 encodes antigenic epitopes recognised by HLA-B4601-restricted cytotoxic T lymphocytes from cancer patients FREE

K Azuma, S Shichijo, H Takedatsu, N Komatsu, H Sawamizu and K Itoh

Br J Cancer 89: 1079-1085; doi:10.1038/sj.bjc.6601203

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Genetics and Genomics

A promoter region of the midkine gene that is frequently expressed in human hepatocellular carcinoma can activate a suicide gene as effectively as the alpha-fetoprotein promoter FREE

M Tomizawa, L Yu, A Wada, T Tamaoki, K Kadomatsu, T Muramatsu, S Matsubara, K Watanabe, M Ebara, H Saisho, S Sakiyama and M Tagawa

Br J Cancer 89: 1086-1090; doi:10.1038/sj.bjc.6601246

Telomerase activity, apoptosis and cell cycle progression in ataxia telangiectasia lymphocytes expressing TCL1 FREE

C Gabellini, A Antonelli, P Petrinelli, A Biroccio, L Marcucci, G Nigro, G Russo, G Zupi and R Elli

Br J Cancer 89: 1091-1095; doi:10.1038/sj.bjc.6601213

Polymorphisms in tumour necrosis factor (TNF) are associated with risk of bladder cancer and grade of tumour at presentation FREE

H P Marsh, N A Haldar, M Bunce, S E Marshall, K le Monier, S L Winsey, K Christodoulos, D Cranston, K I Welsh and A L Harris

Br J Cancer 89: 1096-1101; doi:10.1038/sj.bjc.6601165

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Experimental Therapeutics

n-3 Polyunsaturated fatty acids decrease mucosal/epidermal reactions and enhance antitumour effect of ionising radiation with inhibition of tumour angiogenesis FREE

B Wen, E Deutsch, P Opolon, A Auperin, V Frascogna, E Connault and J Bourhis

Br J Cancer 89: 1102-1107; doi:10.1038/sj.bjc.6601136

Potentiation of tumour apoptosis by human growth hormone via glutathione production and decreased NF-kappaB activity FREE

C Cherbonnier, O Déas, G Carvalho, G Vassal, A Dürrbach, A Haeffner, B Charpentier, J Bénard and F Hirsch

Br J Cancer 89: 1108-1115; doi:10.1038/sj.bjc.6601223

Increased expression of the ubiquitin – proteasome pathway in murine myotubes by proteolysis-inducing factor (PIF) is associated with activation of the transcription factor NF-kappaB FREE

A S Whitehouse and M J Tisdale

Br J Cancer 89: 1116-1122; doi:10.1038/sj.bjc.6601132

TNF-alpha increases human melanoma cell invasion and migration in vitro: the role of proteolytic enzymes FREE

E Katerinaki, G S Evans, P C Lorigan and S MacNeil

Br J Cancer 89: 1123-1129; doi:10.1038/sj.bjc.6601257

An anti-MUC1-antibody–interleukin-2 fusion protein that activates resting NK cells to lysis of MUC1-positive tumour cells FREE

C Heuser, M Ganser, A Hombach, H Brand, G Denton, F-G Hanisch and H Abken

Br J Cancer 89: 1130-1139; doi:10.1038/sj.bjc.6601267

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Letters to the Editor

Irinotecan in patients with relapsed or cisplatin-refractory germ cell cancer: a phase II study of the German Testicular Cancer Study Group FREE

T Powles, J Shamash, D Berney and R T D Oliver

Br J Cancer 89: 1140-1141; doi:10.1038/sj.bjc.6601176

Reply: Irinotecan in patients with relapsed or cisplatin-refractory germ cell cancer: a phase II study of the German Testicular Cancer Study Group FREE

C Kollmannsberger and C Bokemeyer

Br J Cancer 89: 1141-1142; doi:10.1038/sj.bjc.6601177

Changes in BMI after treatment of testicular cancer are due to age and hormonal function and not chemotherapy FREE

R A Huddart and A Norman

Br J Cancer 89: 1143-1144; doi:10.1038/sj.bjc.6601178

Reply: Changes in BMI after treatment of testicular cancer are due to age and hormonal function and not chemotherapy FREE

C Nord and S D Fosså

Br J Cancer 89: 1145; doi:10.1038/sj.bjc.6601179

The published online date indicates the date that the issue is published online and is the first official publication date of the issue. Each print issue of BJC is published one week after it has been published online.

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