Abstract
Weekly treatments with doxorubicin encapsulated in long circulating, sterically stabilised liposomes (DOX-SL) reduced the incidence of metastases from primary mammary carcinoma from 24 of 47 untreated mice to 3 of 23 treated mice. Toxic side-effects were limited to minor, transient weight losses.
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Vaage, J., Donovan, D., Loftus, T. et al. Prevention of metastasis from mouse mammary carcinomas with liposomes carrying doxorubicin. Br J Cancer 72, 1074–1075 (1995). https://doi.org/10.1038/bjc.1995.467
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DOI: https://doi.org/10.1038/bjc.1995.467