Abstract
The neuropathological effects produced by the intrathecal injection of various types of chemical agents have been reviewed. These substances have been utilised for the relief of pain and spasm, for diagnosis and for therapy. Several examples showing the resultant pathological changes have been studied and the effects recorded. The involvement of nerve roots and the periphery of the spinal cord indicates a similar direct toxic effect. After longer survival, fibrotic changes in the pia arachnoid and damage to pial vessels were conspicuous.
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Wolman, L. The neuropathological effects resulting from the intrathecal injection of chemical substances. Spinal Cord 4, 97–115 (1966). https://doi.org/10.1038/sc.1966.9
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DOI: https://doi.org/10.1038/sc.1966.9
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