Genetic improvement of disease resistance in crops often incurs a yield penalty. We identified the ERAD-related ubiquitin-conjugating enzyme OsUBC45 as a positive regulator of rice resistance against multiple pathogens while also improving yield. The underlying mechanism involves OsUBC45 facilitating ubiquitination-mediated degradation of negative regulators of rice yield and immunity.
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References
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This is a summary of: Wang, Y. et al. An ERAD-related ubiquitin-conjugating enzyme boosts broad-spectrum disease resistance and yield in rice. Nat. Food https://doi.org/10.1038/s43016-023-00820-y (2023).
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Overexpressing a ubiquitin-conjugating enzyme improves rice yield and disease resistance. Nat Food 4, 744–745 (2023). https://doi.org/10.1038/s43016-023-00829-3
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DOI: https://doi.org/10.1038/s43016-023-00829-3
