Controlling the stereochemical outcomes of chemical reactions is essential in modern chemical synthesis and manufacturing. Now, a nickel-catalysed, stereoselective hydrometalation and enantioconvergent alkyl–alkyl coupling of alkenyl boronic esters and α-bromo carbonyl derivatives has been achieved to provide single stereoisomers.
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Change history
11 January 2023
A Correction to this paper has been published: https://doi.org/10.1038/s41929-023-00916-5
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Greenhalgh, M.D., Thomas, S.P. Stereoselective alkyl–alkyl cross-coupling. Nat Catal 5, 1079–1080 (2022). https://doi.org/10.1038/s41929-022-00897-x
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DOI: https://doi.org/10.1038/s41929-022-00897-x