Retraction of: Scientific Reports https://doi.org/10.1038/s41598-019-55563-3, published online 18 December 2019


The Authors have retracted this Article.


In the original Article, the Authors reported that low platelet level in HAE patients and high platelet level in hepatocellular carcinoma patients are caused by the differences between these conditions. This did not account for the potential confounding factor that HAE combined with hepatitis B has a low degree of liver cirrhosis whereas hepatocellular carcinoma combined with hepatitis B has a high degree of liver cirrhosis, and so the platelet difference may be reflective of the different degrees of cirrhosis. Since the study did not contain non-hepatitis patients as controls, it was not designed to distinguish between these factors. Additionally, the Authors chose incorrect parameters as input into Lasso regression model, which affects the outcome of the analysis presented in Figure 3. Overall, the Authors cannot guarantee the validity of the results and the conclusions reported in this Article.


All Authors agree with the retraction and its wording.