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Glycobiology

Visualizing the structural diversity of glycoconjugates

Analyzing glycans is challenging because of their structural diversity and complexity and the lack of analytical techniques capable of resolving pools of similar glycan structures. A new method now enables imaging of single glycans, providing direct observation of individual glycans and glycoconjugates.

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Fig. 1: STM imaging of human MUC1 decorated with O-glycans.

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Correspondence to Martina Delbianco or Yu Ogawa.

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Delbianco, M., Ogawa, Y. Visualizing the structural diversity of glycoconjugates. Nat Chem Biol 20, 11–12 (2024). https://doi.org/10.1038/s41589-023-01502-3

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