Author Correction: A central role for JNK in obesity and insulin resistance

Correction to: Nature https://doi.org/10.1038/nature01137 Published online 21 November 2002

It was brought to our attention that there are irregularities with the JNK1/2 western blot data in Figure 4a of our original paper¹. As the raw data for the blots used in the manuscript are no longer available, unfortunately we cannot ascertain the issue with the figure. Figures 1 and 2 of this correction show contemporaneous replicate blots. We apologize for this error.

Fig. 1: JNK activity and protein concentrations in liver, muscle and adipose tissue of lean and obese Jnk1^+/+ (WT) and Jnk1^–/– mice.

In JNK immunoblots (performed by using Pharmingen #666, ref. ²), JNK1 and JNK2 isoforms have relative molecular masses of 56,000–54,000 (both JNK1 and JNK2 contribute to each of these bands, lower being the JNK1) and 46,00–43,000 (both JNK1 and JNK2 contribute to each of these bands, lower being JNK1).

Fig. 2: Western blot analysis of JNK protein concentrations in muscle and adipose tissue of lean and obese Jnk1^+/+ (WT = wild type) and Jnk^–/– mice.

In JNK immunoblots (performed by using Pharmingen #666, ref. ²), JNK1 and JNK2 isoforms have relative molecular masses of 56,000–54,000 (both JNK1 and JNK2 contribute to each of these bands, lower being the JNK1) and 46,00–43,000 (both JNK1 and JNK2 contribute to each of these bands, lower being JNK1).