Olfactory dysfunction is common among individuals with COVID-19; however, the pathophysiology underlying this symptom is not yet clear. In a new study, researchers performed brain MRI in individuals with persistent COVID-19-related olfactory dysfunction and a group of healthy control participants. Gross morphological measures did not differ between the two groups; however, graph analysis of the functional olfactory network showed altered connectivity in the individuals with COVID-19. The researchers highlight the need for further studies with larger sample sizes to confirm their findings.
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Muccioli, L. et al. Cognitive and functional connectivity impairment in post-COVID-19 olfactory dysfunction. Neuroimage Clin. https://doi.org/10.1016/j.nicl.2023.103410 (2023)
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Lemprière, S. Olfactory network function altered in COVID-19. Nat Rev Neurol 19, 326 (2023). https://doi.org/10.1038/s41582-023-00818-x
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DOI: https://doi.org/10.1038/s41582-023-00818-x
