Author Correction: Clonal haematopoiesis-associated, age-related motor deficits caused by monocyte-derived microglia

Correction to: Nature Reviews Immunology https://doi.org/10.1038/s41577-024-00997-8, published online 30 January 2024.

The originally published article contained wording and/or phrasing that could potentially be misleading or unclear. As a result, the following corrections have been made.

• 1. The title has been changed from “Age-related motor deficits caused by clonal haematopoiesis-driven, monocyte-derived microglia” to “Clonal haematopoiesis-associated, age-related motor deficits caused by monocyte-derived microglia”.

• 2. The sentence “To investigate the consequences of CH on monocyte seeding of the ageing brain, the authors performed chimeric bone marrow transplants from mice containing the R822H variant of DNMT3A” has been changed to “To investigate monocyte-mediated CH consequences on the ageing brain, the authors performed chimeric bone marrow transplants from mice expressing the R822H variant of DNMT3A.”

• 3. The sentence “This mutation led to seeding of regions of the ageing brain, including the substantia nigra, with pathogenic monocytes that promoted motor deficits resembling atypical Parkinsonian disorders” has been changed to “Regions of the ageing brain, including the substantia nigra, were seeded with mutant monocyte-derived microglia that promoted motor deficits resembling atypical Parkinsonian disorders.”

• 4. The sentence “This study provides an interesting mechanism by which age-accumulating peripheral monocytes with the DNMT3A R822H mutation seem to drive neuropathology” has been changed to “This study provides an interesting mechanism by which age-accumulating peripheral monocytes with the DNMT3A R822H mutation might drive neuropathology.”

These corrections have been made to the HTML and PDF versions of the article.