Integrin-mediated substrate-rigidity sensing triggers microtubule acetylation, modulating mechanosensitive cellular responses and focal adhesion dynamics, subsequently promoting actomyosin organization and collective cell migration.
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Porshneva, K., Montagnac, G. Mechanotransduction mediated by microtubules. Nat. Mater. 21, 271–272 (2022). https://doi.org/10.1038/s41563-021-01120-1
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DOI: https://doi.org/10.1038/s41563-021-01120-1