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Photochemistry

Illuminating anti-ageing

Nature Chemistry volume 15, pages 451–452 (2023)Cite this article

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Therapies that destroy senescent cells could be used to alleviate age-related disease, yet conventional drugs often suffer from low selectivity and unwanted side effects. Now, a photosensitive agent has been developed that is activated in situ in senescent cells, enabling their selective elimination.

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Fig. 1: Activation of the senotherapeutic prodrug KSL0608-Se.

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Authors and Affiliations

  1. Department of Chemistry, Korea University, Seoul, Republic of Korea

    Yunjie Xu, Jong Seung Kim & Mingle Li

  2. Institute of Microscale Optoelectronics, Shenzhen University, Shenzhen, P. R. China

    Yunjie Xu

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  1. Yunjie Xu
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  2. Jong Seung Kim
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  3. Mingle Li
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Correspondence to Jong Seung Kim or Mingle Li.

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The authors declare no competing interests.

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Xu, Y., Kim, J.S. & Li, M. Illuminating anti-ageing. Nat. Chem. 15, 451–452 (2023). https://doi.org/10.1038/s41557-023-01164-7

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