Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

GENOME ENGINEERING

Plant prime editing goes prime

Nature Plants volume 8, pages 20–22 (2022)Cite this article

Subjects

Incorporation of multiple-nucleotide substitution in prime-editing guide RNAs greatly boosts editing efficiency in rice and maize, advancing precise genome editing in plants.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: An improved plant prime editing system.

References

  1. Molla, K. A., Sretenovic, S., Bansal, K. C. & Qi, Y. Nat. Plants 7, 1166–1187 (2021).

    Article  CAS  Google Scholar 

  2. Anzalone, A. V. et al. Nature 576, 149–157 (2019).

    Article  CAS  Google Scholar 

  3. Xu, W. Nat. Plants https://doi.org/10.1038/s41477-021-01043-4 (2021).

  4. Lin, Q. et al. Nat. Biotechnol. 38, 582–585 (2020).

    Article  CAS  Google Scholar 

  5. Tang, X. et al. Mol. Plant 13, 667–670 (2020).

    Article  CAS  Google Scholar 

  6. Lin, Q. et al. Nat. Biotechnol. 39, 923–927 (2021).

    Article  CAS  Google Scholar 

  7. Zhuang, Y. et al. Nat. Chem. Biol. https://doi.org/10.1038/s41589-021-00889-1 (2021).

    Article  PubMed  PubMed Central  Google Scholar 

  8. Liu, Y. et al. Cell Res. 31, 1134–1136 (2021).

    Article  CAS  Google Scholar 

  9. Nelson, J. W. et al. Nat. Biotechnol. https://doi.org/10.1038/s41587-021-01039-7 (2021).

    Article  PubMed  Google Scholar 

  10. Chen, P. J. et al. Cell 184, 5635–5652.e5629 (2021).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Plant Science and Landscape Architecture, University of Maryland, College Park, MD, USA

    Simon Sretenovic & Yiping Qi

  2. Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD, USA

    Yiping Qi

Authors
  1. Simon Sretenovic
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Yiping Qi
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Yiping Qi.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sretenovic, S., Qi, Y. Plant prime editing goes prime. Nat. Plants 8, 20–22 (2022). https://doi.org/10.1038/s41477-021-01047-0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41477-021-01047-0

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing