A new protein degradation pathway driven by late-endosome-localized MULTIDRUG AND TOXIC COMPOUND EXTRUSION (MATE) efflux transporters opposes autophagy at the onset of senescence. Paradoxically, the new pathway requires a central component of autophagy.
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Zentgraf, U. Tug-of-war during senescence. Nature Plants 5, 129–130 (2019). https://doi.org/10.1038/s41477-019-0369-0
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DOI: https://doi.org/10.1038/s41477-019-0369-0