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Dentipellin, a new antibiotic from culture broth of Dentipellis fragilis

The Journal of Antibiotics volume 74, pages 538–541 (2021)Cite this article

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Abstract

In our effort to find antimicrobial agents from higher fungi, we isolated a new compound, dentipellin (1), along with three known glycosylated diterpenes, erinacines A-C (2-4) from culture broth of Dentipellis fragilis. Their chemical structures were determined by spectroscopic methods including NMR and mass measurements. These compounds exhibited weak antibacterial and antifungal activities.

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Fig. 1
Fig. 2

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Acknowledgements

This work was supported by National University Development Project in 2020. Authors thank Ms. Ji-Young Oh, Center for University-wide Research Facilities (CURF) at Jeonbuk National University, for performing NMR measurements.

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  1. Division of Biotechnology and Advanced Institute of Environmental and Bioscience, College of Environmental and Bioresource Sciences, Jeonbuk National University, Iksan-si, Republic of Korea

    Lee Su Ha, Dae-Won Ki, Ji-Yul Kim, Dae-Cheol Choi, In-Kyoung Lee & Bong-Sik Yun

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  1. Lee Su Ha
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  2. Dae-Won Ki
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Correspondence to Bong-Sik Yun.

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Ha, L.S., Ki, DW., Kim, JY. et al. Dentipellin, a new antibiotic from culture broth of Dentipellis fragilis. J Antibiot 74, 538–541 (2021). https://doi.org/10.1038/s41429-021-00426-1

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