Editor's Focus

Using the Zic3 mouse model of X-linked human heterotaxy, conduction system abnormalities correlated with the severity and location of associated structural cardiac disease identifiable early in development.

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Figure 1

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Non-synonymous GATA6 sequence variants are infrequently found in individuals with congenital heart disease.

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Figure 2

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Ibuprofen treatment for patent ductus arteriosus closure in the preterm baboon neonate did not alter brain growth and development or increase neuropathology.

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Figure 3

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Neither reducing the target temperature nor prolonging the duration further improved ¹H-magnetic resonance spectroscopy, T2-weighted MRI and certain neurobehavorial outcomes in post-ischemic hypothermia in neonatal rats.

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Figure 4

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Allelic variants in PLA2G2A and TLR2 were associated with Gram-positive infections and IL10 was associated with Gram-negative infections in preterm infants, suggesting a role in moderating the predisposition to sepsis.

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Figure 5

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Serial breath sampling for ¹³CO₂ following the intravenous administration of [¹³C]- methionine provides a useful, safe and potentially clinically relevant evaluation of hepatic function in pediatric intestinal, failure-associated, liver disease.

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Figure 6

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