Abstract 152

Background: We previously observed (unpublished data) that plasma 25-hydroxyvitamin D (25OHD) decreased in infants fed cholesterol supplemented preterm formula (PF). Subjects, methods:30 AGA preterm infants were assigned to receive randomly and blindly one of the 3 study PF with different cholesterol content (PF1<3mg/dL, PF2:15mg/dL, PF3:30mg/dL) until they reached theoretical term (TT). Daily oral Vitamin D supplementation (1000IU) was similar in the 3 groups. Plasma 25OHD, 1-25OHD, alkaline phosphatases and cholesterol were measured at time of inclusion (I) and 3 months later (TT). Kruskall-Wallis test was used for comparison of the 3 feeding groups. Results in 20 infants are shown in table (mean±SD): Conclusions: Preliminary results showed no effect of dietary cholesterol intake on vitamin D metabolites in preterm infants fed PF supplemented with 15 or 30 mg/dL cholesterol.[Supported by Milupa research]

Table 1 No caption available.
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