Abstract 101
Introduction: A multiparameter intra-arterial sensor (MPIAS) that continuously measures neonatal arterial blood gases (ABG), has been developed. It employs 3 optical sensors operating as miniature spectrophotometers. The MPIAS is placed in the lumen of the descending aorta via an umbilical arterial catheter (UAC).
Subjects: 27 newborn infants needing intensive care: median (range) birth weight; gestation: 1170g (560-3200); 29 wks (24-40).
Methods: A prospective, non-randomised trial to compared paired, simultaneous pH, PaCO2 and PaO2 readings from the MPIAS and ABG analyser. All infants requiring a UAC were eligible for study. Complications were recorded.
Results: We performed 753 ABG in 3260 hrs of MPIAS monitoring. Overall bias (mean difference) and precision (standard deviation of differences) values were calculated with 95% upper/lower limits of agreement (ULA/LLA): (Table)
Conclusions: Continuous MPIAS ABG monitoring is an exciting development with the potential to reduce blood transfusions and improve ABG homeostasis.
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Morgan, C., Newell, S., Ducker, A. et al. Continuous Neonatal Blood Gas Monitoring Using a Multiparameter Intra-arterial Sensor. Pediatr Res 45, 904 (1999). https://doi.org/10.1203/00006450-199906000-00119
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DOI: https://doi.org/10.1203/00006450-199906000-00119
