A decrease in mineral utilization has been reported in VLBW infants fed HPTF (Rigo Acta Paediatr 1995). Subjects and methods: Bone mineral accretion was evaluated in 16 VLBW infants randomly designed to receive HPTF(n=9, BW=1183±242 g, GA=28.9±1.7 wks) or PTF (n=7, BW=1139±162 g, GA=27.7 ±1.0 wks) from inclusion until theoretical term. Vitamine D supplementation (800 IU/d) was given in both groups. A 3-day metabolic balance was performed at the end of the first month of life and gain in BMC was measured (dual x-ray absorptiometry-DXA) between time of discharge and theoretical term. Table
According to nutritional balance, mineral retention was higher in infants fed HPTF than in those fed PTF; on contrast, gain in BMC between discharge and theoretical term tended to be lower in HPTF group.
In conclusion, further studies on bone mineralization are needed in preterm infants fed HPTF.
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Picaud, JC., Rigo, J., Lapillonne, A. et al. Mineral balance and bone mineral content (BMC) in very low birth weight(VLBW) infants fed new protein hydrolysate preterm formula (HPTF) or standard preterm formula (PTF). 1411. Pediatr Res 41 (Suppl 4), 238 (1997). https://doi.org/10.1203/00006450-199704001-01430
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DOI: https://doi.org/10.1203/00006450-199704001-01430
