Background: ProCT, new marker of bacterial infection, could be more useful than C Reactive Protein (CRP) in neonates suspected of infection but its evaluation has not been performed, especially in infants with RD.
Subjects: 162 neonates were studied prospectively. 25 with maternofoetal infection and 137 non infected (T) (80 without respiratory distress (RD-), 57 with RD (RD+)). ProCT and CRP were measured simultaneously at birth,at H12 of life, and then according to clinical status. (The threshold taken as indicator of bacterial infection: CRP>20mg/1, ProCT>5μg/1).Table
Conclusion: ProCT doesn't appear a useful screening tool for sepsis in neonates.
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Labaune, J., Monneret, G., Bienvenu, F. et al. Procalcitonin (ProCT) as a Marker of Neonatal Infection. 142. Pediatr Res 40, 538 (1996). https://doi.org/10.1203/00006450-199609000-00165
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DOI: https://doi.org/10.1203/00006450-199609000-00165