Abstract
Bronchial asthma, among the allergic diseases has been pointed cut as a cause of growth failure. In a previous report, our group showed that 10% of asthmatic patients from a private clinic (high social level) had short stature (height < 2,5tile). The factors that could be related to growth impairment in atopic children are unknown despite all the research that had been done. In order to evaluate GH secretion through exercise stimulation test, 17 allergic children were submitted to the following protocol: Exercise in a treadmill, during 5 minutes, with a speed calculated based on stature (V(mph)=1,16 + 0,02 × Stature). Blood samples were collected at time O (before exercise) and 10 minutes after resting. The GH was measured through RIA. The children were separated in two groups base on their stature: A) Stature <10tile B) Stature > 25tile. The GH levels didn't show any differences when the two groups were compared (the percentual increment after exercises was 100%). We concluded that the exercise test under appropiate conditions is insatisfactory to distinguish the two population studied. This study points out a possiblity to be investigated of anomalous GH pattern secretion in allergic patients as the cause of short stature, that would not be evident when a stimulation test is done, because the allergic patients under a acute stimulus can secrete GH properly.
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Solé, D., Spiniola-Castro, A., Denardim, O. et al. 1. GROWTH HORMINE (CH) LEVELS IN ALLERGIC CHILDREN BEFORE AND AFTER SLANDARDZED EXERCISE. Pediatr Res 23, 647 (1988). https://doi.org/10.1203/00006450-198806000-00024
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DOI: https://doi.org/10.1203/00006450-198806000-00024