Abstract
Alterations of cation transport across red cell (RC) membranes have been recently described. We investigated the relationship of plasma lipids to the sodium transport system (STS). Na: Na Countertransport (CTT), Na:k contransport (CO), Na: k pump (P), passive permability (PP), cholesterol patients which essential hypertension (EH) of which 24 were normotensive (N) (x 1 : S.D = 10 years 1 0.8, 11 F, 13 M) and 18 were hypertensive (H) control Group, CO was significantly decreased in both N (P < 0.005) and H normal C (166 mg% ± 18) and elevated C (213 mg% ± 26) (P <0.001) their CTT respectively were 255 uM/lc/h ± 110 and 417 uM/lc/hr ± 193 (P <0.005). For children with normal HDLC (50.5 mg% ± 6.7) and decreased HDLC (12 mg% ± 5.2) (P < 0.001), their CTT respectively were 290 uM/lc/h ± 165 and 429 uM/lc/h ± 128 (p <0.025). These findings suggest a possible interation between lipids and STS which should be considered when the STS is evaluated.
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Ginenez, M., Grunfeld, B., Simsolo, R. et al. SODIUM TRANSPCRI SYSTEMS IN THE RED CELL MEMBRANES AND PLASMA LIPIDS IN THE RYPERIENSIVE AND NORMOTENSIVE OFFSPRING OF PATIENTS WITH ESSENTIAL HYPERPTENSION. Pediatr Res 22, 369 (1987). https://doi.org/10.1203/00006450-198709000-00035
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DOI: https://doi.org/10.1203/00006450-198709000-00035