Abstract
Newly designed hydrogels that show stimuli-responsive molecular recognition have been created. Hyperbranched polyethyleneimine (PEI) was modified with methacryl groups and then copolymerized with acrylamide. The resultant copolymer can reversibly bind guest molecules in methanol-water mixed solvent through the interaction between PEI and guest molecules. When the methanol content in the solvent was raised to shrink the polyacrylamide chains, the bound guest molecules were physically entrapped within the hydrogel matrix. These results show that the polyacrylamide chains act as a physical barrier surrounding PEI that can reversibly be opened and closed in response to solvent composition.
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For copolymer A, 3 mL of H2;O and 2 mL of DMSO were used; for copolymer B, 1 mL of H2;O was used.
The maximum binding capacities were not determined in this study.
In this case, stimulus is the change in the solvent composition.
We confirmed that PMC was scarcely released before adding HCl.
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Kanekiyo, Y., Tao, H. & Sellergren, B. Stimuli-Responsive Guest Binding and Releasing by Dendritic Polymer-Based Hydrogels. Polym J 40, 684–687 (2008). https://doi.org/10.1295/polymj.PJ2008018
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DOI: https://doi.org/10.1295/polymj.PJ2008018
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