Abstract
2,4-di-O-benzyl-(1→6)-α-L-glucopyranan, which was synthesized by ringopening polymerization of 1,6-anhydro-3-O-benzoyl-2,4-di-O-benzyl-β-D-glucopyranose (M1) and subsequent selective deprotection of the obtained polymer,1 was glucosylated to give branched polysaccharide having several different anomeric ratios of branching units. β-Glucosidase (cellulase) cleaved only β-glucosidic linkage of the synthesized polysaccharide to give a α-glucose-branched polysaccharide with controlled branching distribution. The sequencial control of the hydroxyl group (branching point) in the polysachharide was attempted also by copolymerization. M1 was found to copolymerize with tri-O-benzyl-levoglucosan (M2) with phosphorus pentafiuoride as catalyst in methylene chloride at −60°C, giving highly stereoregular copolymers. The monomer reactivity ratios calculated by Kelen-Tüdös method were r1=0.27 and r2=2.5.
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Hatanaka, K., Song, SC., Maruyama, A. et al. Attempt to Control Sequence of Branched Polysaccharide with Enzymatic Hydrolysis and/or Copolymerization. Polym J 25, 373–378 (1993). https://doi.org/10.1295/polymj.25.373
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DOI: https://doi.org/10.1295/polymj.25.373