Data from 1,310 men who received prostatectomy has shown that lymphovascular invasion considered 'equivocal' on pathology review was associated with other adverse features, including advanced stage and Gleason grade, and positive surgical margins. Patients with positive nodes and those with equivocal nodes had shorter biochemical-recurrence-free survival than those with negative nodes.
References
Galiabovitch, E. et al. Routinely reported 'equivocal' lymphovascular invasion in prostatectomy specimens is associated with adverse outcomes. BJU Int. http://dx.doi.org/10.1111/bju.13594 (2016)
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Fenner, A. 'Equivocal' lymphovascular invasion?. Nat Rev Urol 13, 495 (2016). https://doi.org/10.1038/nrurol.2016.143
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DOI: https://doi.org/10.1038/nrurol.2016.143
