Once again the question of one versus two 24 h urine collections for diagnosis in kidney stone prevention has been raised. As in all previous studies, no difference is seen in the mean levels of analytes between first and second collections. However, variation within patients is so marked that at least two collections are needed for confidence.
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References
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F. L. Coe declares that he has acted as a consultant for LabCorp.
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Coe, F. A matter of doubt—how best to evaluate stone formers. Nat Rev Urol 7, 483–485 (2010). https://doi.org/10.1038/nrurol.2010.138
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DOI: https://doi.org/10.1038/nrurol.2010.138
