New data—this time from genetic association studies—again implicate the Wnt signaling pathway in the etiology of Dupruyten Disease. Nevertheless, functional studies, and cohorts of different ethnic backgrounds, are needed to distinguish cause and effect in this enigmatic fibrosing disorder.
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The author's research activities are supported by a personal grant from the National Institute of Health Research in the UK.
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Bayat, A. Unpicking Dupruyten Disease etiology—is Wnt the way?. Nat Rev Rheumatol 8, 5–6 (2012). https://doi.org/10.1038/nrrheum.2011.172
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DOI: https://doi.org/10.1038/nrrheum.2011.172
