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Pediatric rheumatic disease

Can molecular profiling predict the future in JIA?

Nature Reviews Rheumatology volume 5, pages 593–594 (2009)Cite this article

Transcriptomics and proteomics are transforming our understanding of juvenile idiopathic arthritis by revealing molecular signatures associated with the various clinical classifications. The challenge now is to find biomarkers that will predict disease course and response to medication in order to improve outcomes for children with arthritis.

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Acknowledgements

P. J. Hunter has been supported by the Arthritis Research Campaign and the Biomedical Research Centre of the Institute of Child Health, University College London and Great Ormond Street Hospital.

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Authors and Affiliations

  1. Rheumatology Unit, Institute of Child Health, University College London, UK

    Patricia J. Hunter & Lucy R. Wedderburn

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  1. Patricia J. Hunter
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  2. Lucy R. Wedderburn
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Correspondence to Lucy R. Wedderburn.

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The authors declare no competing financial interests.

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Hunter, P., Wedderburn, L. Can molecular profiling predict the future in JIA?. Nat Rev Rheumatol 5, 593–594 (2009). https://doi.org/10.1038/nrrheum.2009.215

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