Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Year in Review
  • Published:

Stroke in 2016

Stroke is treatable, but prevention is the key

The past 2 years have seen major breakthroughs in endovascular treatment for acute ischaemic stroke. As highlighted in 2016, we now need to refine the logistics for delivery of this treatment, including patient selection. We should not forget, however, that it is better to prevent strokes in the first place.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: The CHANCE trial substudy.

References

  1. Goyal, M. et al. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet 387, 1723–1731 (2016).

    Article  PubMed  Google Scholar 

  2. Saver, J. L. et al. Time to treatment with endovascular thrombectomy and outcomes from ischemic stroke: a meta-analysis. JAMA 316, 1279–1288 (2016).

    Article  PubMed  Google Scholar 

  3. Lima, F. O. et al. Field assessment stroke triage for emergency destination: a simple and accurate prehospital scale to detect large vessel occlusion strokes. Stroke 47, 1997–2002 (2016).

    Article  PubMed  PubMed Central  Google Scholar 

  4. Amarenco, P. et al. One-year risk of stroke after transient ischemic attack or minor stroke. N. Engl. J. Med. 374, 1533–1542 (2016).

    Article  CAS  PubMed  Google Scholar 

  5. Rothwell, P. M. et al. Effects of aspirin on risk and severity of early recurrent stroke after transient ischaemic attack and ischaemic stroke: time-course analysis of randomised trials. Lancet 388, 365–375 (2016).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Wang, Y. et al. Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N. Engl. J. Med. 369, 11–19 (2013).

    Article  CAS  PubMed  Google Scholar 

  7. Wang, Y. et al. Association between CYP2C19 loss-of-function allele status and efficacy of clopidogrel for risk reduction among patients with minor stroke or transient ischemic attack. JAMA 316, 70–78 (2016).

    Article  CAS  PubMed  Google Scholar 

  8. O'Donnell, M. J. et al. Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case–control study. Lancet 388, 761–775 (2016).

    Article  PubMed  Google Scholar 

  9. Feigin, V. L. et al. Global burden of stroke and risk factors in 188 countries, during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet Neurol. 15, 913–924 (2016).

    Article  PubMed  Google Scholar 

  10. World Stroke Organisation. Campaign Resources Toolkit 2016. WorldStrokeCampaign http://www.worldstrokecampaign.org/get-involved/campaign-toolkit-2016.html (2016).

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ale Algra.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

PowerPoint slides

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Algra, A., Wermer, M. Stroke is treatable, but prevention is the key. Nat Rev Neurol 13, 78–79 (2017). https://doi.org/10.1038/nrneurol.2017.4

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrneurol.2017.4

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing