A long-term outcome analysis in patients with lacunar stroke enrolled in the Secondary Prevention of Small Subcortical Strokes trial highlights the relevance of functional disability after small-vessel strokes. These data support the emerging 'burden of disease' concept in individuals with cerebral microangiopathy, and the role of MRI in outcome prediction.
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Rost, N. More than meets the eye—big consequences of small strokes. Nat Rev Neurol 11, 249–250 (2015). https://doi.org/10.1038/nrneurol.2015.52
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DOI: https://doi.org/10.1038/nrneurol.2015.52