A new study suggests that changes on diffusion tensor imaging might be useful biomarkers for frontotemporal dementia (FTD). Mahoney et al. conducted two scans approximately 1 year apart in 23 patients with FTD and 18 controls. FTD-specific changes between the two scans were most pronounced for fractional anisotropy in the right paracallosal cingulum, which could be used to classify participants with 94% specificity and 63% sensitivity.
References
Mahoney, C. J. et al. Longitudinal diffusion tensor imaging in frontotemporal dementia. Ann. Neurol. 10.1002/ana.24296
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Serial diffusion tensor imaging charts longitudinal course of frontotemporal dementia. Nat Rev Neurol 10, 673 (2014). https://doi.org/10.1038/nrneurol.2014.223
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DOI: https://doi.org/10.1038/nrneurol.2014.223